儿科肝脏类器官移植的伦理挑战。

Ethical challenges for pediatric liver organoid transplantation.

机构信息

Julius Center for Health Sciences and Primary Care, Department of Medical Humanities, University Medical Center Utrecht, 3508 GA, Utrecht, Netherlands.

Department of Pediatrics, Wilhelmina Children's Hospital, University Medical Center Utrecht, 3508 AB, Utrecht, Netherlands.

出版信息

Sci Transl Med. 2020 Jul 15;12(552). doi: 10.1126/scitranslmed.aau8471.

DOI:10.1126/scitranslmed.aau8471

PMID:32669425

Abstract

Liver organoid transplantation may be a less invasive alternative to liver transplant, but is it ethically acceptable to include children with liver disease in a first-in-human clinical trial of this new intervention?

摘要

肝类器官移植可能是一种比肝移植侵入性更小的选择，但是将患有肝病的儿童纳入这种新干预措施的首次人体临床试验中，在伦理上是否可以接受？