小儿肝移植

Pediatric Liver Transplantation.

作者信息

Rawal Nidhi, Yazigi Nada

机构信息

Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Maryland Medical Center, 22 South Green Street, Baltimore, MD 21201, USA.

Pediatric Transplant Hepatology, Department of Transplantation, MedStar Georgetown University Hospital, MedStar Georgetown Transplant Institute, PHC#2, 3800 Reservoir Road, Northwest, Washington, DC 20007, USA.

出版信息

Pediatr Clin North Am. 2017 Jun;64(3):677-684. doi: 10.1016/j.pcl.2017.02.003.

DOI:10.1016/j.pcl.2017.02.003

PMID:28502445

Abstract

Excellent outcomes over the last 3 decades have made liver transplantation the treatment of choice for many advanced liver disorders. This success also opened liver transplantation to new indications such as liver tumors and metabolic disorders. The emergence of such new indications for liver transplantation is bringing a new stream of patients along with disease-specific challenges. The cumulative number of liver transplant recipients is peaking, requiring novel systems of health care delivery that meet the needs of this special patient population. This article reviews updates and new development in pediatric liver transplantation.

摘要

在过去三十年中取得的卓越成果使肝移植成为许多晚期肝脏疾病的首选治疗方法。这一成功也为肝移植开辟了新的适应症，如肝脏肿瘤和代谢紊乱。肝移植这些新适应症的出现带来了新的患者群体以及特定疾病的挑战。肝移植受者的累积数量正在达到峰值，这就需要新的医疗保健系统来满足这一特殊患者群体的需求。本文综述了小儿肝移植的最新进展和新发展。