Mishra Gyan P, Dikshit Harsh K, S V Ramesh, Tripathi Kuldeep, Kumar Ranjeet R, Aski Muraleedhar, Singh Akanksha, Roy Anirban, Kumari Nikki, Dasgupta Uttarayan, Kumar Atul, Praveen Shelly, Nair Ramakrishnan M
Division of Genetics, ICAR-Indian Agricultural Research Institute, New Delhi, India.
Division of Physiology, Biochemistry and PHT, ICAR-Central Plantation, Kasaragod, India.
Front Plant Sci. 2020 Jun 24;11:918. doi: 10.3389/fpls.2020.00918. eCollection 2020.
Globally, yellow mosaic disease (YMD) remains a major constraint of mungbean production, and management of this deadly disease is still the biggest challenge. Thus, finding ways to manage YMD including development of varieties possessing resistance against mungbean yellow mosaic virus (MYMV) and mungbean yellow mosaic India virus (MYMIV) is a research priority for mungbean crop. Characterization of YMD resistance using various advanced molecular and biochemical approaches during plant-virus interactions has unfolded a comprehensive network of pathogen survival, disease severity, and the response of plants to pathogen attack, including mechanisms of YMD resistance in mungbean. The biggest challenge in YMD management is the effective utilization of an array of information gained so far, in an integrated manner for the development of genotypes having durable resistance against yellow mosaic virus (YMV) infection. In this backdrop, this review summarizes the role of various begomoviruses, its genomic components, and vector whiteflies, including cryptic species in the YMD expression. Also, information about the genetics of YMD in both mungbean and blackgram crops is comprehensively presented, as both the species are crossable, and same viral strains are also found affecting these crops. Also, implications of various management strategies including the use of resistance sources, the primary source of inoculums and vector management, wide-hybridization, mutation breeding, marker-assisted selection (MAS), and pathogen-derived resistance (PDR) are thoroughly discussed. Finally, the prospects of employing various powerful emerging tools like translational genomics, and gene editing using CRISPR/Cas9 are also highlighted to complete the YMD management perspective in mungbean.
在全球范围内，黄花叶病（YMD）仍然是绿豆生产的主要限制因素，而管理这种致命疾病仍是最大的挑战。因此，寻找管理黄花叶病的方法，包括培育对绿豆黄花叶病毒（MYMV）和印度绿豆黄花叶病毒（MYMIV）具有抗性的品种，是绿豆作物研究的重点。在植物-病毒相互作用过程中，利用各种先进的分子和生化方法对黄花叶病抗性进行表征，揭示了病原体存活、病害严重程度以及植物对病原体攻击反应的综合网络，包括绿豆黄花叶病抗性机制。黄花叶病管理的最大挑战是如何以综合方式有效利用迄今获得的一系列信息，以培育对黄花叶病毒（YMV）感染具有持久抗性的基因型。在此背景下，本综述总结了各种双生病毒及其基因组组成部分和传毒介体粉虱（包括隐性物种）在黄花叶病表达中的作用。此外，还全面介绍了绿豆和黑豆作物中黄花叶病的遗传学信息，因为这两个物种可以杂交，且发现相同的病毒株也会影响这些作物。此外，还深入讨论了各种管理策略的影响，包括使用抗性资源、接种源的主要来源和介体管理、远缘杂交、诱变育种、分子标记辅助选择（MAS）和病原体衍生抗性（PDR）。最后，还强调了采用各种强大的新兴工具（如转化基因组学和使用CRISPR/Cas9进行基因编辑）来完善绿豆黄花叶病管理前景的可能性。
