Department of Cardiology, Ankara City Hospital, Ankara Turkey.
Department of Ophtalmology, Ankara City Hospital, Ankara Turkey.
Angiology. 2020 Oct;71(9):817-824. doi: 10.1177/0003319720935294. Epub 2020 Jul 16.
Transcatheter aortic valve replacement (TAVR) is associated with clinically significant cerebral microembolism and cognitive status changes. There are no data on the impact of TAVR on retinal layers. We assessed the influence of TAVR on the retinal nerve fiber layer, ganglion cell complex (GCC), and macular thickness (MT) measured by spectral domain optical coherence tomography (SD-OCT). Elderly patients (n = 50) with severe aortic stenosis undergoing TAVR were included in this study (mean age: 78.5 ± 6.9 years). Retinal nerve fiber layer, GCC, and MT were measured with SD-OCT by an ophthalmologist before and on the first day and in the first month after TAVR. The average MT was significantly increased on the first day after TAVR compared with the basal value ( = .04). Ganglion cell complex thickness was significantly thinner on the first day after TAVR than the basal value in the inner inferior quadrant and outer temporal quadrant of the left eye ( = .03 and .04, respectively). Postoperative changes observed on the first day compared with the preoperative period returned to basal values in the first month. In conclusion, TAVR did not cause permanent changes in retinal layers.
经导管主动脉瓣置换术（TAVR）与临床显著的脑微栓塞和认知状态变化有关。目前尚无关于 TAVR 对视网膜层影响的数据。我们评估了 TAVR 对通过谱域光相干断层扫描（SD-OCT）测量的视网膜神经纤维层、节细胞复合体（GCC）和黄斑厚度（MT）的影响。本研究纳入了 50 名接受 TAVR 的老年严重主动脉瓣狭窄患者（平均年龄：78.5 ± 6.9 岁）。眼科医生使用 SD-OCT 在 TAVR 前、第 1 天和第 1 个月测量视网膜神经纤维层、GCC 和 MT。与基础值相比，TAVR 后第 1 天的平均 MT 显著增加（=.04）。与基础值相比，左眼内下象限和外颞象限的 GCC 厚度在 TAVR 后第 1 天明显变薄（分别为=.03 和.04）。与术前相比，术后第 1 天观察到的变化在第 1 个月恢复到基础值。总之，TAVR 不会导致视网膜层的永久性变化。
