Division of General Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
J Altern Complement Med. 2020 Jul;26(7):602-609. doi: 10.1089/acm.2019.0479.
Integrative therapies have been incorporated increasingly into health and wellness in the United States in recent decades. Their potential benefits are under evaluation in various situations, including pain and symptom relief for cancer patients and survivors. This pilot study evaluated whether combining two integrative complementary approaches augments a patient's benefit by reducing postoperative stress, pain, anxiety, muscle tension, and fatigue compared with one integrative complementary approach alone. Patients undergoing autologous tissue breast reconstruction were randomly assigned to one of two postoperative complementary alternative therapies for three consecutive days. All participants were observed for up to 3 months. Forty-two participants were recruited from January 29, 2016 to July 11, 2018. Twenty-one participants were randomly assigned to massage alone and 21 to massage and acupuncture. Stress, anxiety, relaxation, nausea, fatigue, pain, and mood (score 0-10) were measured at enrollment before surgery and postoperative days 1, 2, and 3 before and after the intervention. Patient satisfaction was evaluated. Stress decreased from baseline for both Massage-Only Group and Massage+Acupuncture Group after each treatment intervention. Change in stress score from baseline decreased significantly more in the Massage-Only Group at pretreatment and posttreatment ( = 0.03 and = 0.04). After adjustment for baseline values, change in fatigue, anxiety, relaxation, nausea, pain, and mood scores did not differ between groups. When patients were asked whether they would recommend the study, 100% (19/19) of Massage-Only Group and 94% (17/18) of Massage+Acupuncture Group responded yes ( = 0.49). No additive beneficial effects were observed with addition of acupuncture to massage for pain, anxiety, relaxation, nausea, fatigue, and mood. Combined massage and acupuncture was not as effective in reducing stress as massage alone, although both groups had significant stress reduction. These findings indicate a need for larger studies to explore these therapies further.
在过去的几十年中，综合疗法已越来越多地被纳入美国的健康和养生领域。它们在各种情况下的潜在益处正在评估中，包括癌症患者和幸存者的疼痛和症状缓解。这项初步研究评估了与单独使用一种综合补充疗法相比，同时使用两种综合补充方法是否可以通过减轻术后压力、疼痛、焦虑、肌肉紧张和疲劳来增强患者的受益。接受自体组织乳房重建的患者被随机分配到两种术后补充替代疗法中的一种，连续三天接受治疗。所有参与者都观察了长达 3 个月。
2016 年 1 月 29 日至 2018 年 7 月 11 日期间，共招募了 42 名参与者。21 名参与者被随机分配接受单独按摩，21 名参与者被随机分配接受按摩和针灸。在手术前和术后第 1、2、3 天，在干预前和干预后测量了应激、焦虑、放松、恶心、疲劳、疼痛和情绪（评分 0-10）。评估了患者的满意度。
按摩组和按摩+针灸组在每次治疗干预后，应激值均较基线水平降低。按摩组在治疗前和治疗后的应激评分变化显著大于仅按摩组（ = 0.03 和 = 0.04）。在调整基线值后，两组之间的疲劳、焦虑、放松、恶心、疼痛和情绪评分的变化没有差异。当被问及是否会推荐该研究时，100%（19/19）的仅按摩组和 94%（17/18）的按摩+针灸组回答“是”（ = 0.49）。
与按摩相比，在按摩中加入针灸对疼痛、焦虑、放松、恶心、疲劳和情绪没有观察到附加的有益效果。虽然两组患者的压力均显著降低，但联合使用按摩和针灸在减轻压力方面并不像单独使用按摩那样有效。这些发现表明需要进行更大规模的研究来进一步探索这些疗法。
