Bioengineering and Environmental Science Laboratory, CEEFF, CSIR- Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad 500 007, India.
Bioengineering and Environmental Science Laboratory, CEEFF, CSIR- Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad 500 007, India.
Trends Biotechnol. 2020 Aug;38(8):873-887. doi: 10.1016/j.tibtech.2020.02.004. Epub 2020 Mar 12.
The rapid depletion of petroleum-based fossil fuels has led to the development of alternative fuel and energy solutions from renewable resources. Lipid-derived oleochemicals and sugar-derived bioethanol were initially produced from plant feedstocks, but in the interest of agricultural land conservation and food security, the focus has now shifted toward so-called 'third-generation feedstocks', of which yeasts are a major component. The quest to identify economically lucrative bioprocesses has led to the identification of several nonconventional oleaginous yeast species that have certain advantages over existing model species. Here, we review such underexplored oleaginous yeast species and discuss their potential bioeconomy applications. We also provide a broader perspective on possible avenues for strain improvement to reduce the cost of lipid production.
石油基化石燃料的迅速枯竭促使人们从可再生资源中开发替代燃料和能源解决方案。最初，脂类衍生的油脂化学品和糖衍生的生物乙醇是由植物原料生产的，但为了保护农业土地和粮食安全，现在的重点已经转向所谓的“第三代原料”，其中酵母是主要成分。为了寻找经济上有利可图的生物工艺，人们已经确定了几种具有某些优势的非常规产油酵母物种，这些物种比现有的模式物种更有优势。在这里，我们回顾了这些研究较少的产油酵母物种，并讨论了它们在生物经济中的潜在应用。我们还从更广泛的角度探讨了可能的菌株改良途径，以降低油脂生产成本。
