National Center for Chronic and Noncommunicable Disease Control and Prevention Chinese Center for Disease Control and Prevention Beijing China.
Shandong Center for Disease Control and Prevention Jinan China.
J Am Heart Assoc. 2020 Jul 21;9(14):e014897. doi: 10.1161/JAHA.119.014897. Epub 2020 Jul 17.
Background There have been few studies on the relationship between long-term changes in sodium intake and blood pressure. A method of reducing sodium intake in a population that is known for high-sodium intake based on homemade cooking is also needed. Methods and Results Our study was based on a baseline survey of 15 350 individuals aged 18 to 69 years with multistage random sampling and a 3-year salt-restriction campaign across Shandong Province, China. We included 339 individuals from six districts/counties in this cohort study, and the 24-hour urinary sodium-potassium ratio (Na/K) served as an indicator of sodium intake. The average change in ratio was 2.39 (95% CI, 2.17-2.61) from 6.81 (95% CI, 6.41-7.21) at baseline to 4.41 (95% CI, 4.18-4.64) during the resurvey. Following a reduction from low to high quartiles of urinary Na/K ratio, the average increases were 10.9 (95% CI, 8.9-12.9), 9.2 (95% CI, 6.9-11.5), 6.3 (95% CI, 4.0-8.6), and 5.3 (95% CI, 2.9-7.7) mm Hg for systolic blood pressure ( for trend=0.019) and 3.8 (95% CI, 2.4-5.2), 2.9 (95% CI, 1.7-4.2), 1.6 (95% CI, 0.4-2.8), and -0.3 (95% CI, -1.4-0.8) mm Hg for diastolic blood pressure ( for trend=0.002), respectively. A reduction in salt intake was evident for people using a 2-g salt-restriction spoon for cooking (-3.49 versus -2.22; =0.027) after adjustment of confounding factors, compared with nonusers. Similar findings were obtained for other salt-restriction spoon-based indicators. Conclusions Our study indicated that using a salt-restriction spoon for cooking was associated with reduced salt intake that led to a blunting of blood pressure deterioration. This finding further supports the salt-restriction spoon-based strategy for people whose primary salt intake is from homemade cooking.
关于长期钠摄入量变化与血压之间的关系,研究较少。我们还需要一种基于家庭烹饪的方法来减少钠摄入量,而这些地区的人群钠摄入量本来就很高。
我们的研究基于山东省多阶段随机抽样的基线调查,调查对象为 18 至 69 岁的 15350 人。我们对该队列研究中的 6 个区/县的 339 人进行了分析,24 小时尿钠钾比(Na/K)作为钠摄入量的指标。比值从基线的 6.81(95%置信区间,6.41-7.21)平均变化至复查时的 4.41(95%置信区间,4.18-4.64),为 2.39(95%置信区间,2.17-2.61)。在尿 Na/K 比值从低到高的四分位数中,平均增加量分别为 10.9(95%置信区间,8.9-12.9)、9.2(95%置信区间,6.9-11.5)、6.3(95%置信区间,4.0-8.6)和 5.3(95%置信区间,2.9-7.7)mmHg 的收缩压(趋势=0.019)和 3.8(95%置信区间,2.4-5.2)、2.9(95%置信区间,1.7-4.2)、1.6(95%置信区间,0.4-2.8)和-0.3(95%置信区间,-1.4-0.8)mmHg 的舒张压(趋势=0.002)。在调整混杂因素后,与非使用者相比,使用 2 克限盐勺做饭的人群盐摄入量明显减少(-3.49 比-2.22;=0.027)。基于其他限盐勺指标也得到了类似的发现。
我们的研究表明,使用限盐勺做饭与减少盐摄入量有关,从而降低了血压恶化的程度。这一发现进一步支持了基于限盐勺的策略,适用于主要从家庭烹饪中摄入盐分的人群。