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COVID-19:欧洲呼吸学会国际工作组关于姑息治疗的指南。

COVID-19: guidance on palliative care from a European Respiratory Society international task force.

机构信息

Dept of Research and Development, CIRO, Horn, The Netherlands

Dept of Health Services Research, Care and Public Health Research Institute, Faculty of Health Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.

出版信息

Eur Respir J. 2020 Sep 3;56(3). doi: 10.1183/13993003.02583-2020. Print 2020 Sep.

Abstract

BACKGROUND

Many people are dying from coronavirus disease 2019 (COVID-19), but consensus guidance on palliative care in COVID-19 is lacking. This new life-threatening disease has put healthcare systems under pressure, with the increased need of palliative care provided to many patients by clinicians who have limited prior experience in this field. Therefore, we aimed to make consensus recommendations for palliative care for patients with COVID-19 using the Convergence of Opinion on Recommendations and Evidence (CORE) process.

METHODS

We invited 90 international experts to complete an online survey including stating their agreement, or not, with 14 potential recommendations. At least 70% agreement on directionality was needed to provide consensus recommendations. If consensus was not achieved on the first round, a second round was conducted.

RESULTS

68 (75.6%) experts responded in the first round. Most participants were experts in palliative care, respiratory medicine or critical care medicine. In the first round, consensus was achieved on 13 recommendations based upon indirect evidence and clinical experience. In the second round, 58 (85.3%) out of 68 of the first-round experts responded, resulting in consensus for the 14th recommendation.

CONCLUSION

This multi-national task force provides consensus recommendations for palliative care for patients with COVID-19 concerning: advance care planning; (pharmacological) palliative treatment of breathlessness; clinician-patient communication; remote clinician-family communication; palliative care involvement in patients with serious COVID-19; spiritual care; psychosocial care; and bereavement care. Future studies are needed to generate empirical evidence for these recommendations.

摘要

背景

许多人因 2019 年冠状病毒病(COVID-19)而死亡,但在 COVID-19 姑息治疗方面缺乏共识指南。这种新的危及生命的疾病给医疗保健系统带来了压力,需要临床医生为许多患者提供姑息治疗,而这些医生在该领域的经验有限。因此,我们旨在使用意见趋同推荐和证据(CORE)过程为 COVID-19 患者制定姑息治疗共识建议。

方法

我们邀请了 90 名国际专家完成了一项在线调查,包括对 14 项潜在建议表示同意或不同意。需要至少 70%的一致性才能提供共识建议。如果在第一轮中未达成共识,则进行第二轮。

结果

68 名(75.6%)专家在第一轮中做出了回应。大多数参与者是姑息治疗、呼吸医学或重症监护医学方面的专家。在第一轮中,基于间接证据和临床经验,对 13 项建议达成了共识。在第二轮中,68 名第一轮专家中的 58 名(85.3%)做出了回应,从而对第 14 项建议达成了共识。

结论

该多国家工作组为 COVID-19 患者的姑息治疗提供了共识建议,涉及:预先护理计划;(药物)姑息治疗呼吸困难;临床医生与患者的沟通;远程临床医生与家属的沟通;姑息治疗在严重 COVID-19 患者中的参与;精神关怀;社会心理关怀;以及丧亲关怀。需要进一步的研究为这些建议提供实证证据。

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