McKeon Kathryn P, Jiang Simon H
Department of Renal Medicine, The Canberra Hospital.
Department of Immunology and Infectious Diseases, John Curtin School of Medical Research, Australian National University, Canberra.
Aust Prescr. 2020 Jun;43(3):85-90. doi: 10.18773/austprescr.2020.022. Epub 2020 Jun 2.
Systemic lupus erythematosus should be suspected in individuals with one or more classic symptoms. Diagnosis is made clinically and supported by serology Reducing sun exposure is central to the management of lupus Hydroxychloroquine is first-line treatment unless contraindicated and is useful in almost all manifestations of lupus. Other treatments are titrated against type and severity of organ involvement Monoclonal antibodies have a limited role in the management of lupus
有一个或多个典型症状的个体应怀疑患有系统性红斑狼疮。诊断基于临床症状，并得到血清学检查的支持。减少阳光照射是狼疮治疗的核心。羟氯喹是一线治疗药物，除非有禁忌，对几乎所有狼疮表现都有效。其他治疗方法根据器官受累的类型和严重程度进行调整。单克隆抗体在狼疮治疗中的作用有限。
