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一项居家治疗性运动计划对镰状细胞病(SCD)患者下背部疼痛和功能的有效性。

Effectiveness of a home-based therapeutic exercise program on lower back pain and functionality in Sickle Cell Disease (SCD) patients.

作者信息

Zanoni Camila Tatiana, Galvão Fábio, Maria Renata Manzano, Zulli Roberto, Ricciardi Janaina Bosso, Cliquet Alberto, Saad Sara Teresinha Olalla

机构信息

Universidade Estadual de Campinas (Unicamp), Campinas, SP, Brazil.

Universidade Estadual de Campinas (Unicamp), Campinas, SP, Brazil.

出版信息

Hematol Transfus Cell Ther. 2021 Jul-Sep;43(3):268-279. doi: 10.1016/j.htct.2020.05.004. Epub 2020 Jun 25.

DOI:10.1016/j.htct.2020.05.004
PMID:32680757
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8446254/
Abstract

OBJECTIVE

To investigate the effectiveness of a home-based therapeutic exercise program on lower back pain and functionality of SCD patients.

SETTING

A Hematology and Transfusion Medicine Center, University of Campinas (HEMOCENTRO-UNICAMP).

METHODS

This was a prospective study, with a three-month follow-up of SCD patients with lower back pain. The lumbar spine functionality was evaluated by questionnaires, trunk flexion and extension analyses by fiber-optic-electrogoniometry and measurements of muscle strength of trunk flexor and extensors. The Intervention Group (IG) comprised 18 volunteers, median age 44y (28-58) and the control group (CG) comprised 15 volunteers, median age 42y (19-58), who did not perform exercises. The protocol consisted of daily home-based exercises with two evaluations: at the beginning and end of a three-month program. In order to compare the groups at baseline, the Fisher´s exact test and Mann-Whitney test were used for categorical and numeric variables, respectively. The Wilcoxon test was used for related samples comparing numeric measures of each group over time with a 5% (p < 0.05) significance level.

RESULTS

After the intervention, patients demonstrated a significant improvement, according to the Visual-Analog-Scale (VAS; p = 0.01), Rolland Morris Disability questionnaire (RMDQ; p < 0.01) and trunk flexion and extension muscle strength (p < 0.01). No significant differences were found for the Start-Back-Screening-Tool-Brazil (SBST) and in measures of trunk flexion and extension range-of-motion (RoM).

CONCLUSION

Results suggest that daily home-based exercises for a three-month period ameliorate pain and improve disability related to lower back pain and muscle strength.

摘要

目的

探讨居家治疗性运动方案对镰状细胞病(SCD)患者下背部疼痛及功能的有效性。

背景

坎皮纳斯大学血液学与输血医学中心(HEMOCENTRO - UNICAMP)。

方法

这是一项前瞻性研究,对有下背部疼痛的SCD患者进行为期三个月的随访。通过问卷评估腰椎功能,采用光纤电子测角仪分析躯干屈伸情况,并测量躯干屈伸肌的肌力。干预组(IG)由18名志愿者组成,中位年龄44岁(28 - 58岁),对照组(CG)由15名未进行运动的志愿者组成,中位年龄42岁(19 - 58岁)。方案包括每日居家锻炼,并在三个月方案开始和结束时进行两次评估。为了在基线时比较两组,分别对分类变量和数值变量使用Fisher精确检验和Mann - Whitney检验。使用Wilcoxon检验对相关样本进行分析,比较每组随时间变化的数值指标,显著性水平为5%(p < 0.05)。

结果

干预后,根据视觉模拟量表(VAS;p = 0.01)、罗兰·莫里斯残疾问卷(RMDQ;p < 0.01)以及躯干屈伸肌肌力(p < 0.01),患者有显著改善。在巴西起始-返回-筛查工具(SBST)以及躯干屈伸活动范围(RoM)测量方面未发现显著差异。

结论

结果表明,为期三个月的每日居家锻炼可缓解疼痛,并改善与下背部疼痛和肌肉力量相关的残疾状况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6023/8446254/b3b1680a29aa/gr13.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6023/8446254/57d75632010b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6023/8446254/8c44c2cb727c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6023/8446254/4296c6a78746/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6023/8446254/1569f312f916/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6023/8446254/67aeb43eac4c/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6023/8446254/8f095acf77f7/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6023/8446254/47a6223cc812/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6023/8446254/03bc7f144ba4/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6023/8446254/fd0c2c604ccb/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6023/8446254/c88cb040ad0c/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6023/8446254/1076c1ce2e44/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6023/8446254/984ce9263db2/gr12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6023/8446254/b3b1680a29aa/gr13.jpg

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