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2019冠状病毒病大流行:一项全球卫生负担。

COVID-19 pandemic: A global health burden.

作者信息

Akande Oluwatosin Wuraola, Akande Tanimola Makanjuola

机构信息

Department of Epidemiology and Community Health, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.

出版信息

Niger Postgrad Med J. 2020 Jul-Sep;27(3):147-155. doi: 10.4103/npmj.npmj_157_20.

Abstract

Coronavirus disease 2019 (COVID-19) pandemic began in China with a group of severe pneumonia cases, later identified to be caused by the severe acute respiratory syndrome coronavirus 2 in December 2019. Thailand reported the first COVID-19 case outside of China on 13 January 2020, Africa reported its first case in Egypt on 14 February 2020 and Nigeria reported its index case of COVID-19 on 27 February 2020. Virtually, all countries in the world are affected, with over 5 million cases reported globally. A literature search was conducted using publications from academic databases and websites of relevant organisations. The disease is associated with typical and atypical signs and symptoms, mimicking other common illnesses. Nigeria is now in the phase of widespread community transmission as almost all the states have reported confirmed cases. The pandemic has shown a wide range of case-fatality rate (CFR) globally; this is postulated to be related to the demographics, existing health systems and probably other unidentified factors. There has been a steady increase in the burden caused by the disease in Nigeria with a relatively stable CFR, which is lower than the global CFR. Health systems have responded with the guidelines for prevention, management, and surveillance of the disease, while effort is being put in place to find a vaccine and a specific therapy for the cure of the disease. The pandemic has had a severe effect on health systems globally, including an unintended disruption in the service delivery of other diseases. It has the potential to disrupt the weak health system in Nigeria significantly. As such, a combination of non-pharmaceutical preventive measures that are cost-effective needs to be scaled up to prevent it from further weakening the existing health system.

摘要

2019年冠状病毒病(COVID-19)大流行始于中国,最初是一批严重肺炎病例,后于2019年12月被确定为由严重急性呼吸综合征冠状病毒2引起。泰国于2020年1月13日报告了中国境外首例COVID-19病例,非洲于2020年2月14日在埃及报告了首例病例,尼日利亚于2020年2月27日报告了其COVID-19首例病例。实际上,世界上几乎所有国家都受到影响,全球报告的病例超过500万例。我们使用学术数据库和相关组织网站上的出版物进行了文献检索。该疾病与典型和非典型的体征及症状相关,容易与其他常见疾病相混淆。尼日利亚目前正处于社区广泛传播阶段,因为几乎所有州都报告了确诊病例。全球范围内,该大流行呈现出广泛的病死率(CFR);据推测,这与人口统计学、现有卫生系统以及可能其他未明确的因素有关。尼日利亚因该疾病造成的负担一直在稳步增加,病死率相对稳定,低于全球病死率。卫生系统已出台针对该疾病的预防、管理和监测指南,同时正在努力寻找治疗该疾病的疫苗和特效疗法。该大流行对全球卫生系统产生了严重影响,包括意外扰乱了其他疾病的服务提供。它有可能严重扰乱尼日利亚薄弱的卫生系统。因此,需要扩大具有成本效益的非药物预防措施的组合,以防止其进一步削弱现有的卫生系统。

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