Human Science Special Assigned Lab., Toyota Central R&D Labs., Inc, Aichi, Japan.
Chubu Medical Center for Prolonged Traumatic Brain Dysfunction, Kizawa Memorial Hospital, Minokamo, Japan.
Comput Methods Biomech Biomed Engin. 2020 Nov;23(15):1236-1246. doi: 10.1080/10255842.2020.1795142. Epub 2020 Jul 20.
Mild traumatic brain injury (TBI), including concussions, can cause symptoms affecting physical or cognitive domains in the acute and chronic phases. In this study, we investigated the dynamic deformation of the brain stem, which might be important for these symptoms, using a human brain finite element model through reconstruction simulations of rear-end collisions in three different velocities. In all simulations, high maximum principal strain values were observed at the midbrain that were higher than those in the corpus callosum. These findings could provide some mechanical insights into brain disorders associated with mild TBI.
轻度创伤性脑损伤（TBI），包括脑震荡，可在急性期和慢性期引起影响身体或认知领域的症状。在这项研究中，我们通过重建三种不同速度的追尾碰撞模拟，使用人体大脑有限元模型研究了脑干的动态变形，这可能对这些症状很重要。在所有模拟中，中脑的最大主应变值都很高，高于胼胝体的值。这些发现可为与轻度 TBI 相关的脑疾病提供一些力学见解。
