Lee Beom-Joon, Lee Ju Ah, Kim Kwan-Il, Choi Jun-Yong, Jung Hee-Jae
Division of Allergy, Immune and Respiratory System, Department of Internal Medicine, College of Korean Medicine, Kyung Hee University Seoul, Republic of Korea.
Hwapyeong Institute of Integrative Medicine, Incheon, Republic of Korea.
Integr Med Res. 2020 Sep;9(3):100470. doi: 10.1016/j.imr.2020.100470. Epub 2020 Jul 5.
The Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2), which originated in Wuhan, Hubei Province, China in late December 2019, is the cause of ongoing pandemic. We analyzed the symptoms of SARS-CoV-2, a classification of the Chinese medicine dialectic and treatment regimen, and promptly enacted the recommendation of Korean medicine preparations in herbal medicine covered under domestic medical insurance benefits depending on the circumstances in our country.
The clinical practice guideline (CPG) for the treatment of SARS-CoV-2 was developed based on consensus from a group of experts.
Two kinds of herbal medicines (HM) were recommended for the prevention of SARS-CoV-2; Youngyopaedoc-san plus Bojungikgitang, and Youngyopaedoc-san plus Saengmaek-san. Two herbal preparations were recommended for people with a history of exposure to SARS-CoV-2; Youngyopaedoc-san plus Bulhwangeumjeonggi-san, and Youngyopaedoc-san plus Bojungikgi-tang. Three herbal preparations were recommended for mildly symptomatic COVID-19 patients; Youngyopaedoc-san plus Galgunhaegui-tang was recommended for those without pneumonia with wind-warmth disease invading the lungs; Sosiho-tang plus Bulhwangeumjeonggi-san was recommended for those with dampness-heat disease in the lungs. For the recovery stage, Samchulkunbi-tang plus Saengmaek-san, or Samchulkunbi-tang plus Chungseuiki-tang was recommended.
The CPG was developed to guide the use of Korean herbal medicine in the treatment of SARS-CoV-2, and it is expected that this will be the basis for providing proper treatment of similar infectious diseases in the future.
严重急性呼吸综合征冠状病毒2(SARS-CoV-2)于2019年12月底起源于中国湖北省武汉市,是当前全球大流行的病因。我们分析了SARS-CoV-2的症状、中医辩证分类及治疗方案,并根据我国国情,适时制定了国内医疗保险覆盖的韩医草药制剂的使用建议。
基于一组专家的共识制定了SARS-CoV-2治疗的临床实践指南(CPG)。
推荐两种草药用于预防SARS-CoV-2;小青龙加补中益气汤,以及小青龙加生脉散。对于有SARS-CoV-2暴露史的人群推荐两种草药制剂;小青龙加白虎承气汤,以及小青龙加补中益气汤。对于轻症COVID-19患者推荐三种草药制剂;对于无肺炎的风温犯肺型患者推荐小青龙加葛根黄芩黄连汤;对于肺有湿热证的患者推荐四逆散加白虎承气汤。对于恢复期,推荐三物黄芩汤加生脉散,或三物黄芩汤加柴胡桂枝干姜汤。
制定CPG以指导韩医草药在SARS-CoV-2治疗中的应用,预计这将成为未来对类似传染病进行恰当治疗的基础。