Brinch M, Isager T, Tolstrup K
Department of Child Psychiatry, Rigshospitalet, Copenhagen, Denmark.
Acta Psychiatr Scand. 1988 May;77(5):611-7. doi: 10.1111/j.1600-0447.1988.tb05175.x.
A follow-up carried out on an average 12.5 years after hospital contact of 151 patients with a former diagnosis of anorexia nervosa (AN), aimed at reproduction outcome. None of the 11 males had children. Fifty of the 140 women had given birth to a total of 86 children, which is approximately one third of the expected fertility. Involuntary childlessness was of the same size as found in the background population. The rate of prematurity among the offspring was twice the expected and perinatal lethality six times the expected. Mentally the mothers did well, both during pregnancy and the post partum period. They breast-fed their children for the same mean time as did other women, and the development of the children did not differ from that found in a background population. More women in the group of mothers than in the group of non-mothers had better scores of all-round functioning at follow-up.
对151名曾被诊断为神经性厌食症（AN）的患者进行了随访，平均在出院接触后12.5年进行，目的是了解生殖结局。11名男性均无子女。140名女性中有50名共生育了86个孩子，这大约是预期生育能力的三分之一。非自愿无子女的情况与背景人群中发现的情况相同。后代的早产率是预期的两倍，围产期死亡率是预期的六倍。母亲们在精神上在孕期和产后都表现良好。她们母乳喂养孩子的平均时间与其他女性相同，孩子的发育与背景人群中发现的情况没有差异。在随访中，母亲组中功能全面得分较好的女性比非母亲组更多。
