Instituto Paranaense de Otorrinolaringologia (IPO), Curitiba, PR, Brazil.
Pontifícia Universidade Católica do Paraná (PUC-PR), Curitiba, PR, Brazil.
Braz J Otorhinolaryngol. 2022 Mar-Apr;88(2):243-250. doi: 10.1016/j.bjorl.2020.05.023. Epub 2020 Jul 7.
Chronic rhinosinusitis is an inflammatory condition of the nasal cavity and the paranasal sinuses that requires multifactorial treatment. Xylitol can be employed with nasal irrigation and can provide better control of the disease.
To evaluate the association between the effects of nasal lavage with saline solution compared to nasal lavage with a xylitol solution.
Fifty-two patients, divided into two groups (n = 26 in the "Xylitol" group and n = 26 in the "Saline solution" group) answered questionnaires validated in Portuguese (NOSE and SNOT-22) about their nasal symptoms and general symptoms, before and after endonasal endoscopic surgery and after a period of 30 days of nasal irrigation.
The "Xylitol" group showed significant improvement in pain relief and nasal symptom reduction after surgery and nasal irrigation with xylitol solution (p < 0.001). The "Saline solution" group also showed symptom improvement, but on a smaller scale.
This study suggests that the xylitol solution can be useful in the postoperative period after endonasal endoscopic surgery, because it leads to a greater reduction in nasal symptoms.
慢性鼻-鼻窦炎是一种鼻腔和鼻窦的炎症性疾病，需要多因素治疗。木糖醇可与鼻腔冲洗一起使用，并能更好地控制疾病。
评估与生理盐水鼻腔冲洗相比，用木糖醇溶液进行鼻腔冲洗的效果差异。
52 名患者被分为两组（“木糖醇”组 n=26，“生理盐水”组 n=26），在鼻内镜手术后和 30 天鼻腔冲洗后，用经过验证的葡萄牙语问卷（NOSE 和 SNOT-22）评估他们的鼻部症状和一般症状。
“木糖醇”组在手术后和使用木糖醇溶液鼻腔冲洗后疼痛缓解和鼻部症状减轻方面有显著改善（p<0.001）。“生理盐水”组也表现出症状改善，但程度较小。
本研究表明，在鼻内镜手术后的术后期间，木糖醇溶液可能有用，因为它能更有效地减轻鼻部症状。
