Department of Public Health, Aarhus University, Aarhus C, Denmark.
Department of Clinical Medicine, Diagnostic Center, Silkeborg Regional Hospital, Silkeborg, Denmark.
J Strength Cond Res. 2022 Jul 1;36(7):1801-1809. doi: 10.1519/JSC.0000000000003735. Epub 2020 Jul 20.
Dalgaard, LB, Jørgensen, EB, Oxfeldt, M, Dalgaard, EB, Johansen, FT, Karlsson, M, Ringgaard, S, and Hansen, M. Influence of second generation oral contraceptive use on adaptations to resistance training in young untrained women. J Strength Cond Res 36(7): 1801-1809, 2022-The study purpose was to determine effects of using second generation oral contraceptives (OC) on muscle adaptations to resistance training in young untrained women. Twenty users and 18 nonusers of OC completed a 10-week supervised progressive resistance training program. Before and after the intervention, muscle cross-sectional area (mCSA) of the quadriceps was measured using magnetic resonance imaging and muscle fiber CSA (fCSA) was determined by immunohistochemistry. In addition, body composition (DXA, fat mass/fat-free mass), maximal isometric muscle strength (dynamometry), 5 repetition maximum (5RM) leg press strength, counter movement jump (CMJ) height, and average power using a modified Wingate test were determined. Serum hormone analysis ensured OC compliance and 4-day food records documented dietary intake. After the training period, quadriceps mCSA (OC: 11.0 ± 6.0% vs. non-OC: 9.2 ± 5.0%, p = 0.001), type II fCSA (OC: 19.9 ± 7.9% vs. non-OC: 16.6 ± 7.2%, p = 0.05), muscle strength (knee extension, knee flexion and 5RM, p < 0.001), and functional power (CMJ, AP, p < 0.001) were significantly increased with no significant difference between the groups. However, a tendency toward a greater increase in fat-free mass (FFM) in the OC group was observed (OC: 3.7 ± 3.8% vs. non-OC: 2.7 ± 3.5%, p = 0.08). Collectively, use of second generation OCs in young untrained women did not significantly improve adaptations to 10 weeks of resistance training compared with nonusers. The trend toward greater gains in FFM in the OC group warrant future studies.
达尔加德，LB，约根森，EB，奥克斯菲尔德，M，达尔加德，EB，约翰森，FT，卡尔森，M，林加德，S，汉森，M. 第二代口服避孕药的使用对年轻未经训练女性抗阻训练适应的影响。J 力量与体能研究 36(7):1801-1809, 2022-本研究旨在确定在年轻未经训练女性中使用第二代口服避孕药（OC）对阻力训练适应的影响。20 名 OC 用户和 18 名非 OC 用户完成了 10 周的监督性渐进式抗阻训练计划。干预前后，使用磁共振成像测量股四头肌的肌肉横截面积（mCSA），通过免疫组织化学测定肌纤维 CSA（fCSA）。此外，还测定了身体成分（DXA、脂肪量/去脂体重）、最大等长肌肉力量（测力）、5 次重复最大（5RM）腿举力量、反跳高度和使用改良 Wingate 测试的平均功率。血清激素分析确保 OC 依从性，4 天的食物记录记录饮食摄入。训练结束后，股四头肌 mCSA（OC：11.0±6.0%vs.非 OC：9.2±5.0%，p=0.001）、II 型 fCSA（OC：19.9±7.9%vs.非 OC：16.6±7.2%，p=0.05）、肌肉力量（膝关节伸展、膝关节屈曲和 5RM，p<0.001）和功能功率（CMJ、AP，p<0.001）均显著增加，但两组间无显著差异。然而，观察到 OC 组去脂体重（FFM）增加的趋势更大（OC：3.7±3.8%vs.非 OC：2.7±3.5%，p=0.08）。总之，与非使用者相比，年轻未经训练的女性使用第二代 OCs 并没有显著改善 10 周的抗阻训练适应。OC 组 FFM 增加幅度更大的趋势需要进一步研究。
