Sharma Loknandini, Agarwal Reetu, Chopra Ajay, Mitra Barnali
Department of Dermatology, Base Hospital Delhi Cantt, New Delhi, India.
Department of Paediatrics, Base Hospital Delhi Cantt, New Delhi, India.
Indian Dermatol Online J. 2020 May 10;11(3):361-366. doi: 10.4103/idoj.IDOJ_340_19. eCollection 2020 May-Jun.
Fixed food eruption (FFE) is a rare type of hypersensitivity reaction occurring after ingestion of some food items in the form of recurrent erythematous patches, bullae, vesicle, or pustule at the same site after ingestion of same or related food products. Various items listed responsible for causing FFE include tree nuts, groundnuts, legumes, lentils, eggs, fruits like kiwi, strawberry, tonic water, and tartrazine. Its more commonly reported in developed countries with no Indian studies as of yet. We studied the clinical spectrum and prevalence of FFE in a tertiary care hospital.
To study the prevalence and pattern of FFE after eliminating all other possible causes including drug rash.
A cross-section observational study of 27 consecutive patients suspected to have fixed food eruption after eliminating all possibilities of any drug reaction to the best of our knowledge. Informed consent was obtained from the patients, and ethical clearance was taken from the hospital ethical committee.
A total of 27 patients were studied out of which 18 (66.66%) were females and 9 (33.33%) were males. The prevalence of fixed food eruption was calculated to be 0.072%.Fixed food eruption was noted secondary to cashew nuts (14.8%), almonds (7.4%), walnut (7.4%), pistachio (3.7%), strawberry (3.7%), kiwi (3.7%), and cheese crisps (3.7%).
This observational study highlights the varied patterns of fixed food eruptions as well as the burden of disease in population secondary to certain diets.
固定性食物疹（FFE）是一种罕见的超敏反应类型，在摄入相同或相关食品后，会在同一部位反复出现红斑、大疱、水疱或脓疱。被认为可引发FFE的各类食物包括坚果、花生、豆类、小扁豆、鸡蛋、猕猴桃、草莓等水果、奎宁水和酒石黄。在发达国家，FFE的报告更为常见，目前尚无印度的相关研究。我们在一家三级护理医院研究了FFE的临床谱和患病率。
在排除包括药疹在内的所有其他可能病因后，研究FFE的患病率和模式。
进行一项横断面观察性研究，研究对象为连续27例疑似患有固定性食物疹的患者，尽我们所知排除了任何药物反应的所有可能性。获得了患者的知情同意，并获得了医院伦理委员会的伦理批准。
共研究了27例患者，其中女性18例（66.66%），男性9例（33.33%）。固定性食物疹的患病率经计算为0.072%。发现固定性食物疹继发于腰果（14.8%）、杏仁（7.4%）、核桃（7.4%）、开心果（3.7%）、草莓（3.7%）、猕猴桃（3.7%）和奶酪薯片（3.7%）。
这项观察性研究突出了固定性食物疹的多样模式以及某些特定饮食导致的人群疾病负担。
