Shen Hui, Chen Meijuan, Cui Donghong
Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shanghai Key Laboratory of Psychotic Disorders, Shanghai, China.
Gen Psychiatr. 2020 Jul 13;33(4):e100214. doi: 10.1136/gpsych-2020-100214. eCollection 2020.
In recent years, research on meditation as an important alternative therapy has developed rapidly and been widely applied in clinical medicine. Mechanism studies of meditation have also developed progressively, showing that meditation has great impact on brain structure and function, and epigenetic and telomere regulation. In line with this, the application of meditation has gradually been expanded to mental illness, most often applied for major depressive disorders and substance-related and addictive disorders. The focus of this paper is to illustrate the biological mechanisms of meditation and its application in mental disorders.
近年来,作为一种重要替代疗法的冥想研究发展迅速,并在临床医学中得到广泛应用。冥想的机制研究也在逐步发展,表明冥想对大脑结构与功能、表观遗传和端粒调节有重大影响。与此相符的是,冥想的应用已逐渐扩展到精神疾病领域,最常应用于重度抑郁症以及物质相关和成瘾性障碍。本文的重点是阐述冥想的生物学机制及其在精神障碍中的应用。