Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education and Research, Bhangagarh, Guwahati 781032, Assam, India.
Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education and Research, Bhangagarh, Guwahati 781032, Assam, India.
Complement Ther Clin Pract. 2014 Feb;20(1):74-80. doi: 10.1016/j.ctcp.2013.10.001. Epub 2013 Oct 18.
Meditation is a complex mental practice involving changes in sensory perception, cognition, hormonal and autonomic activity. It is widely used in psychological and medical practices for stress management as well as stress mediated mental disorders like depression. A growing body of literature has shown that meditation has profound effects on numerous physiological systems that are involved in the pathophysiology of major depressive disorder (MDD). Although meditation-based interventions have been associated with improvement in depressive symptoms and prevention of relapse, the physiological mechanisms underlying the therapeutic effects of meditation are not clearly defined and even paradoxical. This paper reviews many of the physiological abnormalities found in cytokine & stress mediated depression and the reversal of these anomalies by different meditation techniques.
冥想是一种复杂的心理练习，涉及感觉感知、认知、激素和自主活动的变化。它被广泛应用于心理和医学实践中，用于管理压力以及由压力引起的精神障碍，如抑郁症。越来越多的文献表明，冥想对涉及重度抑郁症（MDD）病理生理学的许多生理系统有深远的影响。尽管基于冥想的干预措施与改善抑郁症状和预防复发有关，但冥想治疗效果的生理机制尚不清楚，甚至存在矛盾。本文综述了细胞因子和应激介导的抑郁症中发现的许多生理异常，以及不同冥想技术对这些异常的逆转。
