Kwon Younghoon, Logan Jeongok, Pusalavidyasagar Snigdha, Kasai Takatoshi, Cheong Crystal Sj, Lee Chi-Hang
Department of Medicine, University of Virginia, Charlottesville, VA 22908 USA.
University of Virginia School of Nursing, Charlottesville, VA 22908 USA.
Sleep Med Res. 2019 Dec;10(2):67-74. doi: 10.17241/smr.2019.00493. Epub 2019 Dec 31.
Scientific investigations in the past few decades have supported the important role of sleep in various domains of health. Sleep apnea is a highly prevalent yet underdiagnosed sleep disorder representing a valid cardiovascular risk factor, particularly for hypertension. While several studies have demonstrated the benefits of sleep apnea treatment on subclinical cardiovascular measures, there is a paucity of studies proving reduction of cardiovascular events and mortality. Sufficient and high-quality sleep is also important in the maintenance of cardiovascular health. Future investigations should focus on improving identification of patients at greatest risk of adverse cardiovascular s sequalae of sleep apnea and testing the therapeutic benefit of sleep apnea treatment in this vulnerable group.
过去几十年的科学研究证实了睡眠在健康的各个领域所起的重要作用。睡眠呼吸暂停是一种高度普遍但诊断不足的睡眠障碍,是一个有效的心血管危险因素,尤其是对于高血压而言。虽然多项研究已证明睡眠呼吸暂停治疗对亚临床心血管指标有益,但证明可减少心血管事件和死亡率的研究却很匮乏。充足且高质量的睡眠对维持心血管健康也很重要。未来的研究应着重于更好地识别睡眠呼吸暂停导致心血管不良后果风险最高的患者,并测试睡眠呼吸暂停治疗对这一脆弱群体的治疗效果。