Division of Child Neurology, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.
School of Medicine, University of Virginia, Charlottesville, Virginia.
J Clin Sleep Med. 2021 Aug 1;17(8):1591-1598. doi: 10.5664/jcsm.9252.
Sleep quality in patients studied with laboratory-based polysomnography may differ from sleep quality in patients studied at home but remains clinically relevant and important to describe. We assessed objective sleep quality and explored factors associated with poor sleep in patients undergoing laboratory-based polysomnography.
We reviewed diagnostic polysomnography studies from a 10-year period at a single sleep center. Total sleep time (TST) and sleep efficiency (SE) were assessed as markers of sleep quality. Poor sleep was defined as TST ≤ 4 hours or SE ≤ 50%. Multivariable analysis was performed to determine associations between objective sleep quality as an outcome and multiple candidate predictors including age, sex, race, body mass index, comorbidities, severity of obstructive sleep apnea, and central nervous system medications.
Among 4957 patients (age 53 ± 15 years), average TST and median SE were 5.8 hours and 79%, respectively. There were 556 (11%) and 406 (8%) patients who had poor sleep based on TST and SE, respectively. In multivariable analysis, those who were older (per 10 years: 1.48 [1.34, 1.63]), male (1.38 [1.14,1.68]), and had severe obstructive sleep apnea (1.76 [1.28, 2.43]) were more likely to have short sleep. Antidepressant use was associated with lower odds of short sleep (0.77 [0.59,1.00]). Older age (per 10 years: 1.48 [1.34, 1.62]), male sex (1.34 [1.07,1.68]), and severe obstructive sleep apnea (2.16 [1.47, 3.21]) were associated with higher odds of poor SE.
We describe TST and SE from a single sleep center cohort. Multiple demographic characteristics were associated with poor objective sleep in patients during laboratory-based polysomnography.
Harrison EI, Roth RH, Lobo JM, et al. Sleep time and efficiency in patients undergoing laboratory-based polysomnography. . 2021;17(8):1591-1598.
在进行基于实验室的多导睡眠图检查的患者中，睡眠质量可能与在家中进行睡眠检查的患者不同，但描述基于实验室的多导睡眠图检查的睡眠质量仍具有临床意义且非常重要。我们评估了客观睡眠质量，并探讨了与基于实验室的多导睡眠图检查患者睡眠质量差相关的因素。
我们回顾了单中心睡眠中心 10 年期间的诊断性多导睡眠图研究。总睡眠时间（TST）和睡眠效率（SE）被评估为睡眠质量的指标。睡眠质量差定义为 TST≤4 小时或 SE≤50%。多变量分析用于确定客观睡眠质量（作为结果）与包括年龄、性别、种族、体重指数、合并症、阻塞性睡眠呼吸暂停严重程度和中枢神经系统药物在内的多个候选预测因子之间的关联。
在 4957 名患者（年龄 53±15 岁）中，平均 TST 和中位数 SE 分别为 5.8 小时和 79%。根据 TST 和 SE，分别有 556（11%）和 406（8%）名患者睡眠质量差。多变量分析显示，年龄每增加 10 岁（1.48[1.34，1.63]）、男性（1.38[1.14，1.68]）和严重阻塞性睡眠呼吸暂停（1.76[1.28，2.43]）的患者更有可能睡眠短暂。使用抗抑郁药与较短的睡眠时间（0.77[0.59，1.00]）相关。年龄每增加 10 岁（1.48[1.34，1.62]）、男性（1.34[1.07，1.68]）和严重阻塞性睡眠呼吸暂停（2.16[1.47，3.21]）与 SE 较差的几率更高相关。
我们描述了来自单个睡眠中心队列的 TST 和 SE。在进行基于实验室的多导睡眠图检查的患者中，多项人口统计学特征与客观睡眠质量差相关。
Harrison EI, Roth RH, Lobo JM, et al. Sleep time and efficiency in patients undergoing laboratory-based polysomnography.. 2021;17(8):1591-1598.
