Hobart M J, Lachmann P J, Calne R Y
J Exp Med. 1977 Aug 1;146(2):629-30. doi: 10.1084/jem.146.2.629.
The allotype of the sixth component of complement was determined in a patient before and after liver transplantation. The C6 phenotype changed from A before transplantation to B (the donor phenotype) within 10 days of the transplant and remained wholly of the donor phenotype at 17 wk. This demonstrates that the liver is the exclusive or predominant site of C6 synthesis in vivo in man.
在一位肝移植患者肝移植前后对补体第六成分的同种异型进行了测定。移植后10天内,C6表型从移植前的A变为B(供体表型),并在17周时完全保持供体表型。这表明肝脏是人体内补体C6在体内合成的唯一或主要部位。