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犬补体第六成分(C6)的多态性

Polymorphism of the sixth component of complement (C6) in the dog.

作者信息

Anderson J E, Ladiges W C, Giblett E R, Weiden P, Storb R

出版信息

Biochem Genet. 1983 Feb;21(1-2):155-60. doi: 10.1007/BF02395399.

Abstract

Isoelectric focusing was used to identify five alleles at the locus determining the production of the sixth component of complement (C6) in the dog. Four of these alleles, C6(1), C6(2), C6(4), and C6(5), were studied in family pedigrees and shown to be inherited in a codominant autosomal fashion. All alleles except for C6(4) occurred commonly in the multiple breeds tested.

摘要

采用等电聚焦法在犬中鉴定决定补体第六成分(C6)产生的基因座上的五个等位基因。对其中四个等位基因C6(1)、C6(2)、C6(4)和C6(5)进行了家系研究,结果表明它们以共显性常染色体方式遗传。除C6(4)外,所有等位基因在测试的多个品种中普遍存在。

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