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病例报告:1 例 HIV 合并感染且 CD4 T 淋巴细胞计数正常的新型冠状病毒肺炎(COVID-19)患者。

Case report: one case of coronavirus disease 2019 (COVID-19) in a patient co-infected by HIV with a normal CD4 T cell count.

机构信息

Department of Urology, Beijing You'an Hospital, Capital Medical University, Beijing, China.

Department of Critical care medicine of liver disease, Beijing You'an Hospital, Capital Medical University, Beijing, China.

出版信息

AIDS Res Ther. 2020 Jul 23;17(1):46. doi: 10.1186/s12981-020-00301-3.

Abstract

BACKGROUND

The COVID-19 has been a severe pandemic all around the world. Nowadays the patient with co-infection of HIV and SARS-CoV-2 was rarely reported. Here we reported a special case with HIV and SARS-CoV-2 co-infection, which showed a prolonged viral shedding duration.

CASE PRESENTATION

The patient was infected with HIV 8 years ago through sexual transmission and had the normal CD4T cell count. She was found SARS-CoV-2 positive using real-time Polymerase Chain Reaction (RT-PCR) during the epidemic. Most importantly, the patient had a prolonged viral shedding duration of SARS-CoV-2 about 28 days.

CONCLUSION

The viral shedding duration may be prolonged in people living with HIV. The 14 days isolation strategy might not be long enough for them. The isolation or discharge of these patients needs further confirmation for preventing epidemics.

摘要

背景

COVID-19 已在全球范围内造成严重大流行。目前,HIV 和 SARS-CoV-2 合并感染的患者报道较少。我们在此报告了一例 HIV 和 SARS-CoV-2 合并感染的特殊病例,其病毒脱落持续时间较长。

病例介绍

该患者 8 年前通过性传播感染 HIV,CD4T 细胞计数正常。在疫情期间,她通过实时聚合酶链反应(RT-PCR)发现 SARS-CoV-2 呈阳性。最重要的是,该患者 SARS-CoV-2 的病毒脱落持续时间约为 28 天。

结论

HIV 感染者的病毒脱落持续时间可能会延长。14 天的隔离策略对他们来说可能不够长。这些患者的隔离或出院需要进一步确认,以防止疫情发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f9f/7376905/462be5fe139e/12981_2020_301_Fig1_HTML.jpg

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