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噬血细胞综合征与新型冠状病毒肺炎

Hemophagocytic syndrome and COVID-19.

作者信息

Lima Ricardo, Filho Célio Cortinhas, Ferreira Filho Carlos Martins, Vaisman Mauricio, Cossenza Alexandre, Rebello Caroline Pinto, Leite Carolina de Andrade, de Oliveira Tavares Danilo, Ramalho Julia Falconiere

机构信息

ICU, Samaritano Hospital UHG, Brazil.

Surgery and Critical Care, Department of Federal University of State of Rio de Janeiro, Brazil.

出版信息

Respir Med Case Rep. 2020 Jul 10;31:101162. doi: 10.1016/j.rmcr.2020.101162. eCollection 2020.

DOI:10.1016/j.rmcr.2020.101162
PMID:32704472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7347481/
Abstract

The case of a woman hospitalized due to COVID-19 is presented. The patient developed a severe macrophage activation syndrome diagnosed by bone marrow biopsy, which did not respond to immunoglobulin therapy.

摘要

本文介绍了一名因新冠肺炎住院的女性病例。该患者通过骨髓活检被诊断为严重巨噬细胞活化综合征，对免疫球蛋白治疗无反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6030/7369594/ede484a34139/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6030/7369594/ede484a34139/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6030/7369594/ede484a34139/gr1.jpg

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本文引用的文献

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Bone marrow histomorphological criteria can accurately diagnose hemophagocytic lymphohistiocytosis.骨髓组织形态学标准能够准确诊断噬血细胞性淋巴组织细胞增生症。
Haematologica. 2018 Oct;103(10):1635-1641. doi: 10.3324/haematol.2017.186627. Epub 2018 Jun 14.
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Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study.
COVID-19 后生存患者经骨髓活检诊断噬血细胞性淋巴组织细胞增生症：病例报告及迷你综述。
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Cureus. 2022 Feb 26;14(2):e22620. doi: 10.7759/cureus.22620. eCollection 2022 Feb.
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