Ryder R W, Buxton A E, Wachsmuth I K, Mason E, Barrett F F
J Pediatr. 1977 Aug;91(2):302-3. doi: 10.1016/s0022-3476(77)80837-8.
During an outbreak of diarrhea in a special care nursery caused by heat-stable enterotoxigenic Escherichia coli (serotype 078:H11:K80), nine (4.3%) of the 205 infants in the nursery developed necrotizing enterocolitis. Cases of necrotizing enterocolitis were not significantly more common in infants colonized or infected with these organisms; heat-stable enterotoxigenic E. coli was isolated from 5(56%) of nine cases of necrotizing ecterocolitis and from 27(38%) of the 71 infants without necrotizing enterocolitis who were also cultured. Our findings suggest that caution should be taken in implicating enterotoxigenic E. coli as a cause of necrotizing enterocolitis.
在一家特别护理托儿所爆发由耐热肠毒素性大肠杆菌（血清型O78:H11:K80）引起的腹泻期间，托儿所205名婴儿中有9名（4.3%）患上坏死性小肠结肠炎。坏死性小肠结肠炎病例在定植或感染这些细菌的婴儿中并不显著更常见；在9例坏死性小肠结肠炎病例中的5例（56%）以及在71名未患坏死性小肠结肠炎且也接受培养的婴儿中的27例（38%）中分离出了耐热肠毒素性大肠杆菌。我们的研究结果表明，在将产肠毒素大肠杆菌视为坏死性小肠结肠炎的病因时应谨慎。
