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全民医疗体系中儿童睾丸固定术的时机:国际行政数据队列研究

Timing of paediatric orchidopexy in universal healthcare systems: international administrative data cohort study.

作者信息

Jay M A, Arat A, Wijlaars L, Ajetunmobi O, Fitzpatrick T, Lu H, Lei S, Skerritt C, Goldfeld S, Gissler M, Gunnlaugsson G, Hrafn Jónsson S, Hjern A, Guttmann A, Gilbert R

机构信息

Population Policy and Practice Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.

Clinical Epidemiology, Department of Medicine, Karolinska Institutet and Centre for Health Equity Studies, Stockholm, Sweden.

出版信息

BJS Open. 2020 Jul 24;4(6):1117-24. doi: 10.1002/bjs5.50329.

Abstract

BACKGROUND

International guidelines in 2008 recommended orchidopexy for undescended testis at 6-12 months of age to reduce the risk of testicular cancer and infertility. Using administrative data from England, Finland, Ontario (Canada), Scotland and Sweden (with data from Victoria (Australia) and Iceland in supplementary analyses), the aim of this study was to investigate compliance with these guidelines and identify potential socioeconomic inequities in the timing of surgery before 1 and 3 years.

METHODS

All boys born in 2003-2011 with a diagnosis code of undescended testis and procedure codes indicating orchidopexy before their fifth birthday were identified from administrative health records. Trends in the proportion of orchidopexies performed before 1 and 3 years of age were investigated, as were socioeconomic inequities in adherence to the guidelines.

RESULTS

Across all jurisdictions, the proportion of orchidopexies occurring before the first birthday increased over the study period. By 2011, from 7·6 per cent (Sweden) to 27·9 per cent (Scotland) of boys had undergone orchidopexy by their first birthday and 71·5 per cent (Sweden) to 90·4 per cent (Scotland) by 3 years of age. There was limited evidence of socioeconomic inequities for orchidopexy before the introduction of guidelines (2008). Across all jurisdictions for boys born after 2008, there was consistent evidence of inequities in orchidopexy by the first birthday, favouring higher socioeconomic position. Absolute differences in these proportions between the highest and lowest socioeconomic groups ranged from 2·5 to 5·9 per cent across jurisdictions.

CONCLUSION

Consistent lack of adherence to the guidelines across jurisdictions questions whether the guidelines are appropriate.

摘要

背景

2008年的国际指南建议在6至12个月大时对隐睾进行睾丸固定术,以降低患睾丸癌和不育症的风险。本研究利用来自英格兰、芬兰、安大略省(加拿大)、苏格兰和瑞典的行政数据(补充分析中使用了来自维多利亚州(澳大利亚)和冰岛的数据),旨在调查对这些指南的遵守情况,并确定在1岁和3岁之前手术时机方面潜在的社会经济不平等。

方法

从行政健康记录中识别出所有在2003年至2011年出生、诊断代码为隐睾且程序代码表明在其五岁生日前进行了睾丸固定术的男孩。调查了在1岁和3岁之前进行睾丸固定术的比例趋势,以及遵守指南方面的社会经济不平等情况。

结果

在所有司法管辖区,一岁前进行睾丸固定术的比例在研究期间有所增加。到2011年,一岁前接受睾丸固定术的男孩比例从7.6%(瑞典)到27.9%(苏格兰),到三岁时从71.5%(瑞典)到90.4%(苏格兰)。在指南出台前(2008年),睾丸固定术存在社会经济不平等的证据有限。在2008年之后出生的男孩的所有司法管辖区,有一致的证据表明一岁前进行睾丸固定术存在不平等,有利于较高的社会经济地位。各司法管辖区中最高和最低社会经济群体在这些比例上的绝对差异在2.5%至5.9%之间。

结论

各司法管辖区一直缺乏对指南的遵守,这让人质疑这些指南是否合适。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f43c/7709362/d6d87f6a5e40/BJS5-4-1117-g001.jpg

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