Wang Yunxia, Zhang Yong, Qiao Zheng, Wang Wanjun
Department of Mechanical Engineering, Louisiana State University, Baton Rouge, LA 70803, USA.
Micromachines (Basel). 2020 Jul 17;11(7):695. doi: 10.3390/mi11070695.
Homogeneous mixing of microscopic volume fluids at low Reynolds number is of great significance for a wide range of chemical, biological, and medical applications. An efficient jet mixer with arrays of micronozzles was designed and fabricated using additive manufacturing (three-dimensional (3D) printing) technology for applications in centrifugal microfluidic platforms. The contact surface of miscible liquids was enhanced significantly by impinging plumes from two opposite arrays of micronozzles to improve mixing performance. The mixing efficiency was evaluated and compared with the commonly used Y-shaped micromixer. Effective mixing in the jet mixer was achieved within a very short timescale (3s). This 3D printed jet mixer has great potential to be implemented in applications by being incorporated into multifarious 3D printing devices in microfluidic platforms.
在低雷诺数下实现微观体积流体的均匀混合对于广泛的化学、生物和医学应用具有重要意义。利用增材制造（三维（3D）打印）技术设计并制造了一种带有微喷嘴阵列的高效射流混合器，用于离心微流控平台。通过来自两个相对微喷嘴阵列的冲击羽流显著增强了互溶液体的接触表面，以提高混合性能。对混合效率进行了评估，并与常用的Y形微混合器进行了比较。射流混合器在非常短的时间尺度（3秒）内实现了有效混合。这种3D打印的射流混合器通过集成到微流控平台中的各种3D打印设备中，在应用中具有很大的潜力。
