Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA; Division of Quantitative Sciences, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA.
Trends Genet. 2020 Nov;36(11):807-809. doi: 10.1016/j.tig.2020.07.001. Epub 2020 Jul 22.
The causes for disparities in implementation of precision medicine are complex, due in part to differences in clinical care and a lack of engagement and recruitment of under-represented populations in studies. New tools and large genetic cohorts can change these circumstances and build access to personalized medicine for disadvantaged populations.
造成精准医学实施差异的原因很复杂,部分原因是临床护理的差异,以及代表性不足的人群在研究中的参与度和招募不足。新工具和大型遗传队列可以改变这些情况,为弱势群体建立获得个性化医疗的途径。