Department of Ophtalmology, Sir JJ Group of Hospitals, Mumbai, Maharashtra, India.
Indian J Ophthalmol. 2020 Aug;68(8):1681-1683. doi: 10.4103/ijo.IJO_2074_19.
Ocular metastatic lesions from head to neck region are rare. 55 years old male patient presented with loss of vision, pain, and proptosis of the left eye. The patient was known case of laryngeal squamous carcinoma underwent laryngectomy 1 and half years back followed by chemoradiation. Well-defined scleral nodule extending from limbus to optic nerve was noted. In view of no other metastatic focus other than left eye on positron emission tomography (PET) scan, left eye enucleation was performed. Histopathological examination (HPE) showed squamous cell carcinoma. The patient received external beam radiotherapy (EBRT) for left eye orbit. This is the first well-documented proven case of uveoscleral metastasis from laryngeal carcinoma.
眼部转移性病变来自头颈部区域较为罕见。一名 55 岁男性患者因左眼视力丧失、疼痛和突出就诊。该患者为 1 年半前因喉鳞癌行喉切除术并接受放化疗的已知病例。左眼从角膜缘到视神经有明确的巩膜结节。正电子发射断层扫描(PET)显示除左眼外无其他转移性病灶,因此行左眼眼球摘除术。组织病理学检查(HPE)显示为鳞状细胞癌。患者接受左眼眼眶外照射放疗(EBRT)。这是首例有明确记录的喉癌葡萄膜巩膜转移的病例。