Istituto di Microbiologia, Università Cattolica del Sacro Cuore, Rome, Italy.
Dipartimento Scienze della salute della donna, del bambino e di sanità pubblica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Pediatr Pulmonol. 2020 Oct;55(10):2547-2555. doi: 10.1002/ppul.24978. Epub 2020 Jul 30.
Since its first description in China, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide being declared a pandemic by the World Health Organization. More than 10.3 million people have been infected and more than 506 000 people died. However, SARS-CoV-2 had a lower impact on the pediatric population. Only about 1% to 2% of infected people are children and few deaths under the age of 14 are described so far. In this article, we discuss microbiological and immunological characteristics of SARS-CoV-2 infection in children highlighting the main differences from adult SARS-CoV-2 infection.
自在中国首次描述以来，严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）已在全球范围内传播，并被世界卫生组织宣布为大流行。超过 1030 万人受到感染，超过 50.6 万人死亡。然而，SARS-CoV-2 对儿科人群的影响较小。只有约 1%至 2%的感染者为儿童，迄今为止，描述的 14 岁以下死亡人数很少。在本文中，我们讨论了 SARS-CoV-2 感染在儿童中的微生物学和免疫学特征，重点强调了与成人 SARS-CoV-2 感染的主要区别。
