Aoki Megan M, Emery R J Neil, Anjard Christophe, Brunetti Craig R, Huber Robert J
Department of Biology, Trent University, Peterborough, ON, Canada.
Institut Lumière Matière, CNRS UMR 5306, Université Claude Bernard Lyon 1, Université de Lyon, Lyon, France.
Front Cell Dev Biol. 2020 Jun 19;8:511. doi: 10.3389/fcell.2020.00511. eCollection 2020.
Cytokinins (CKs) are a diverse group of evolutionarily significant growth-regulating molecules. While the CK biosynthesis and signal transduction pathways are the most well-understood in plant systems, these molecules have been identified in all kingdoms of life. This review follows the recent discovery of an expanded CK profile in the social amoeba, . A comprehensive review on the present knowledge of CK biosynthesis, signal transduction, and CK-small molecule interactions within members of Dictyostelia will be summarized. In doing so, the utility of social amoebae will be highlighted as a model system for studying the evolution of these hormone-like signaling agents, which will set the stage for future research in this area.
细胞分裂素（CKs）是一类在进化上具有重要意义的多种生长调节分子。虽然CK生物合成和信号转导途径在植物系统中是最广为人知的，但这些分子已在所有生命王国中被鉴定出来。本综述追踪了近期在社会变形虫中发现的扩展的CK谱。将总结关于盘基网柄菌属成员内CK生物合成、信号转导以及CK与小分子相互作用的现有知识的全面综述。在此过程中，将突出社会变形虫作为研究这些类激素信号分子进化的模型系统的效用，这将为该领域的未来研究奠定基础。
