• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Demonstration of focal physiologic in-vivo somatostatin receptor expression in the caput epididymis of the testes on Ga-DOTANOC PET/CT and Lu-DOTATATE post-therapy whole body scintigraphy.利用镓-多柔比星PET/CT及镥-多柔比星治疗后全身闪烁扫描术，证明睾丸附睾头部存在局灶性生理性体内生长抑素受体表达。
Asia Ocean J Nucl Med Biol. 2020 Spring;8(2):132-135. doi: 10.22038/AOJNMB.2020.44324.1297.
2
Somatostatin receptor imaging in non-(131)I-avid metastatic differentiated thyroid carcinoma for determining the feasibility of peptide receptor radionuclide therapy with (177)Lu-DOTATATE: low fraction of patients suitable for peptide receptor radionuclide therapy and evidence of chromogranin A level-positive neuroendocrine differentiation.奥曲肽受体显像在非(131)I 摄取的转移性分化型甲状腺癌中评估(177)Lu-DOTATATE 肽受体放射性核素治疗的可行性：适合肽受体放射性核素治疗的患者比例较低，且存在嗜铬粒蛋白 A 水平阳性神经内分泌分化的证据。
Clin Nucl Med. 2014 Jun;39(6):505-10. doi: 10.1097/RLU.0000000000000429.
3
Comparison of 68Ga-DOTANOC and 68Ga-DOTATATE PET/CT within patients with gastroenteropancreatic neuroendocrine tumors.胃肠胰神经内分泌肿瘤患者中 68Ga-DOTANOC 与 68Ga-DOTATATE PET/CT 的比较。
J Nucl Med. 2013 Mar;54(3):364-72. doi: 10.2967/jnumed.112.111724. Epub 2013 Jan 7.
4
The Bad Berka dose protocol: comparative results of dosimetry in peptide receptor radionuclide therapy using (177)Lu-DOTATATE, (177)Lu-DOTANOC, and (177)Lu-DOTATOC.巴德贝卡剂量方案：使用（177）镥-奥曲肽、（177）镥-多他奈和（177）镥-多他曲进行肽受体放射性核素治疗的剂量测定比较结果。
Recent Results Cancer Res. 2013;194:519-36. doi: 10.1007/978-3-642-27994-2_30.
5
Prevalence of hitherto unknown brain meningioma detected on Ga-DOTATATE positron-emission tomography/computed tomography in patients with metastatic neuroendocrine tumor and exploring potential of Lu-DOTATATE peptide receptor radionuclide therapy as single-shot treatment approach targeting both tumors.在转移性神经内分泌肿瘤患者中，通过镓- DOTATATE正电子发射断层扫描/计算机断层扫描检测到迄今未知的脑脑膜瘤，并探索镥- DOTATATE肽受体放射性核素治疗作为针对两种肿瘤的单次治疗方法的潜力。
World J Nucl Med. 2019 Apr-Jun;18(2):160-170. doi: 10.4103/wjnm.WJNM_39_18.
6
Quantitative and qualitative intrapatient comparison of 68Ga-DOTATOC and 68Ga-DOTATATE: net uptake rate for accurate quantification.68Ga-DOTATOC与68Ga-DOTATATE的患者体内定量和定性比较：用于准确量化的净摄取率
J Nucl Med. 2014 Feb;55(2):204-10. doi: 10.2967/jnumed.113.126177. Epub 2013 Dec 30.
7
Hot Embolus Artifact Mimicking Disease Progression in Post-therapy Lu-DOTATATE Scan: Incremental Value of SPECT/CT.热栓塞伪影在治疗后镥-奥曲肽扫描中模拟疾病进展：SPECT/CT的增量价值
Nucl Med Mol Imaging. 2023 Jun;57(3):159-161. doi: 10.1007/s13139-023-00789-3. Epub 2023 Feb 18.
8
MIB-1 Index-Stratified Assessment of Dual-Tracer PET/CT with Ga-DOTATATE and F-FDG and Multimodality Anatomic Imaging in Metastatic Neuroendocrine Tumors of Unknown Primary in a PRRT Workup Setting.在肽受体放射性核素治疗（PRRT）检查背景下，对镓-多柔比星（Ga-DOTATATE）和氟-氟代脱氧葡萄糖（F-FDG）双示踪剂PET/CT及多模态解剖成像进行MIB-1指数分层评估，用于不明原发灶的转移性神经内分泌肿瘤。
J Nucl Med Technol. 2017 Mar;45(1):34-41. doi: 10.2967/jnmt.116.185777. Epub 2017 Feb 2.
9
The NETPET Score: Combining FDG and Somatostatin Receptor Imaging for Optimal Management of Patients with Metastatic Well-Differentiated Neuroendocrine Tumors.NETPET 评分：结合 FDG 和生长抑素受体显像优化治疗转移性高分化神经内分泌肿瘤。
Theranostics. 2017 Mar 1;7(5):1159-1163. doi: 10.7150/thno.19588. eCollection 2017.
10
Use of radioactive substances in diagnosis and treatment of neuroendocrine tumors.放射性物质在神经内分泌肿瘤诊断和治疗中的应用。
Scand J Gastroenterol. 2015 Jun;50(6):740-7. doi: 10.3109/00365521.2015.1033454.

引用本文的文献

1
Nephrotoxicity after radionuclide therapies.放射性核素治疗后的肾毒性。
Transl Oncol. 2022 Jan;15(1):101295. doi: 10.1016/j.tranon.2021.101295. Epub 2021 Nov 27.

本文引用的文献

1
68Ga-DOTANOC PET/CT in an Atypical Extraskeletal Paravertebral Hemangioma Mimicking as Neurogenic Tumor in a Known Case of Breast Cancer.68Ga-DOTANOC PET/CT 在一非典型椎旁外生性血管外皮细胞瘤中的应用，该肿瘤在已知乳腺癌病例中表现为神经源性肿瘤。
Clin Nucl Med. 2019 May;44(5):e364-e366. doi: 10.1097/RLU.0000000000002521.
2
Ectopic Cushing Syndrome (ECS): 68Ga-DOTANOC PET/CT Localizes the Site of Ectopic Adrenocorticotropic Hormone Production.异位库欣综合征（ECS）：68Ga-DOTANOC PET/CT 定位异位促肾上腺皮质激素产生的部位。
Clin Nucl Med. 2018 Oct;43(10):769-770. doi: 10.1097/RLU.0000000000002217.
3
Incidental Meningioma on Ga-DOTANOC Positron-Emission Tomography.镓-多他胺正电子发射断层扫描中偶然发现的脑膜瘤。
Indian J Nucl Med. 2018 Apr-Jun;33(2):182. doi: 10.4103/ijnm.IJNM_162_17.
4
Imaging-Guided Use of Combined Lu-DOTATATE and Capecitabine Therapy in Metastatic Mediastinal Paraganglioma.影像引导下联合使用镥[¹⁷⁷Lu]奥曲肽和卡培他滨治疗转移性纵隔副神经节瘤
J Nucl Med Technol. 2017 Dec;45(4):314-316. doi: 10.2967/jnmt.117.197400. Epub 2017 Aug 10.
5
Pediatric Neuroendocrine Carcinoid Tumors: Review of Diagnostic Imaging Findings and Recent Advances.小儿神经内分泌类癌肿瘤：诊断性影像学检查结果及最新进展综述
AJR Am J Roentgenol. 2017 Apr;208(4):868-877. doi: 10.2214/AJR.16.17287. Epub 2017 Feb 15.
6
Somatostatin receptor imaging with 68Ga DOTATATE PET/CT: clinical utility, normal patterns, pearls, and pitfalls in interpretation.68Ga-DOTATATE PET/CT 进行生长抑素受体显像：临床应用、正常表现、解读要点及陷阱。
Radiographics. 2015 Mar-Apr;35(2):500-16. doi: 10.1148/rg.352140164.
7
Neuroendocrine tumor imaging with 68Ga-DOTA-NOC: physiologic and benign variants.68Ga-DOTA-NOC 神经内分泌肿瘤成像：生理性和良性变异。
AJR Am J Roentgenol. 2014 Dec;203(6):1317-23. doi: 10.2214/AJR.14.12588.
8
Somatostatin receptor-based PET/CT of intracranial tumors: a potential area of application for 68 Ga-DOTA peptides?基于生长抑素受体的颅内肿瘤 PET/CT：68Ga-DOTA 肽的潜在应用领域？
AJR Am J Roentgenol. 2013 Dec;201(6):1340-7. doi: 10.2214/AJR.13.10987.
9
Gallium-68 DOTATOC PET/CT in vivo characterization of somatostatin receptor expression in the prostate.镓-68 DOTATOC正电子发射断层显像/X线计算机体层成像（PET/CT）对前列腺中生长抑素受体表达的体内特征分析
Cancer Biother Radiopharm. 2014 Apr;29(3):108-15. doi: 10.1089/cbr.2013.1570. Epub 2014 Jan 22.
10
Diagnostic accuracy of (68)Ga-DOTANOC PET/CT imaging in pheochromocytoma.（68）Ga-DOTANOC PET/CT 成像在嗜铬细胞瘤中的诊断准确性。
Eur J Nucl Med Mol Imaging. 2014 Mar;41(3):494-504. doi: 10.1007/s00259-013-2598-1. Epub 2013 Oct 25.

利用镓-多柔比星PET/CT及镥-多柔比星治疗后全身闪烁扫描术，证明睾丸附睾头部存在局灶性生理性体内生长抑素受体表达。

Demonstration of focal physiologic in-vivo somatostatin receptor expression in the caput epididymis of the testes on Ga-DOTANOC PET/CT and Lu-DOTATATE post-therapy whole body scintigraphy.

作者信息

Parihar Ashwin Singh, Sood Apurva, Sood Ashwani, Gulati Ajay, Mittal Bhagwant Rai

机构信息

Departments of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Department of Radiodiagnosis, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Asia Ocean J Nucl Med Biol. 2020 Spring;8(2):132-135. doi: 10.22038/AOJNMB.2020.44324.1297.

DOI:10.22038/AOJNMB.2020.44324.1297
PMID:32715001
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7354247/
Abstract

We present the case of a 60-year-old man with metastatic neuroendocrine tumor of the ileum following ileal resection, being evaluated for Lu-based peptide receptor radionuclide therapy. Ga-DOTANOC PET/CT showed focal increased tracer uptake in the scrotal region without any morphologic changes on the corresponding CT images. Similar increased tracer uptake was seen on post-therapy whole-body imaging following Lu-DOTATATE therapy. An USG guided FNA revealed no malignant cells on cytopathologic examination. This case illustrates that focal testicular tracer uptake, may not always be pathological and can represent a normal physiologic variant, similar to the diffuse testicular somatostatin receptor expression as previously reported in literature.

摘要

我们报告一例60岁男性，患有回肠转移性神经内分泌肿瘤，在回肠切除术后接受基于镥的肽受体放射性核素治疗评估。镓-多他萘辛PET/CT显示阴囊区域有局灶性示踪剂摄取增加，而相应的CT图像上无任何形态学改变。在镥-多他肽治疗后的治疗后全身成像中也可见类似的示踪剂摄取增加。超声引导下细针穿刺活检的细胞病理学检查未发现恶性细胞。该病例表明，睾丸局灶性示踪剂摄取不一定总是病理性的，可能代表一种正常的生理变异，类似于文献中先前报道的弥漫性睾丸生长抑素受体表达。