Karan Nupur, Siddiqui Suhail, Sharma Kailash S, Pantvaidya Gouri H, Divatia Jigeeshu V, Kulkarni Atul P
Department of Neuroanaesthesia and Critical Care, NIMHANS, Bangalore, India.
Department of Critical Care Medicine, King George's Medical University Faculty of Medical Sciences, Lucknow, Uttar Pradesh, India.
Head Neck. 2020 Oct;42(10):2968-2974. doi: 10.1002/hed.26354. Epub 2020 Jul 27.
Identification of risk factors for perioperative complications helps in the prognostication. We wanted to determine whether Physiological and Operative Severity Score for the enumeration of mortality and morbidity (POSSUM) and Portsmouth-POSSUM (P-POSSUM) can be used in patients undergoing head and neck oncosurgery.
We conducted a retrospective analysis of 1265 patients after they had major head and neck oncosurgeries. Demographic, surgical and outcome data was collected. We separately analyzed data for patients who had undergone cancer surgery for oral cavity, pharynx, and larynx. We calculated the POSSUM and P-POSSUM scores.
POSSUM scoring system had moderate discrimination (AUC = 0.61) and good calibration (P = .36) for the entire study cohort and in the subgroup. Since there were no deaths in the entire cohort, we were not able to check predictive ability of the scores, for mortality.
We found that POSSUM had moderate discrimination and good calibration for morbidity prediction in head and neck cancer surgeries, as well as for the selected subgroup.
识别围手术期并发症的危险因素有助于进行预后评估。我们想确定用于计算死亡率和发病率的生理和手术严重程度评分系统（POSSUM）以及朴茨茅斯 - POSSUM（P - POSSUM）是否可用于接受头颈肿瘤手术的患者。
我们对1265例接受重大头颈肿瘤手术后的患者进行了回顾性分析。收集了人口统计学、手术和结局数据。我们分别分析了接受口腔、咽和喉癌手术患者的数据。我们计算了POSSUM和P - POSSUM评分。
对于整个研究队列及其亚组，POSSUM评分系统具有中等区分度（AUC = 0.61）和良好的校准度（P = 0.36）。由于整个队列中无死亡病例，我们无法检验该评分对死亡率的预测能力。
我们发现POSSUM对头颈癌手术以及所选亚组的发病率预测具有中等区分度和良好的校准度。
