Kitajima Kazuhiro, Futani Hiroyuki, Tsuchitani Tatsuya, Takahashi Yoshiyuki, Tachibana Toshiya, Yamakado Koichiro
Department of Radiology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501 Japan.
Hell J Nucl Med. 2020 May-Aug;23(2):133-137. doi: 10.1967/s002449912102. Epub 2020 Jul 27.
To evaluate the ability of quantitative values obtained with bone single photon emission computed tomography/computed tomography (SPECT/CT) to differentiate benign from malignant cartilaginous bone neoplasms.
Bone SPECT/CT scans of 10 patients with 8 benign cartilaginous bone neoplasms (4 enchondromas, 1 periosteal chondroma, 1 osteochondroma, 1 bizarre parosteal osteochondromatous proliferation, 1 chondroblastoma) and 2 malignant cartilaginous bone neoplasms (1 periosteal chondrosarcoma, 1 chondrosarcoma) were retrospectively analyzed with maximum standardized uptake value (SUVmax), mean SUV (SUVmean), metabolic bone volume (MBV), and total bone uptake (TBU) of primary lesions.
Mean SUVmax of 8 benign and 2 malignant cartilaginous bone neoplasms were 1.93±1.02 (range 0.59-3.41) and 6.07±0.86 (5.46-6.67), respectively with no overlap (P=0.028). Mean SUVmean of those were 1.24±0.71 (range 0.36-2.36) and 4.05±0.30 (3.84-4.26), respectively with no overlap (P=0.00036). Mean MBV of those were 7.17±4.19 (range 3.17-13.77) and 10.29±10.05 (3.19-17.4), respectively with no significant difference (P=0.74). Mean TBU of those were 9.22±8.31 (range 1.15-23.61) and 43.19±43.7 (12.26-74.13), respectively with no significant difference (P=0.47).
Standardized uptake value obtained with bone SPECT/CT may be useful to differentiate benign from malignant cartilaginous bone neoplasms, thus helping the orthopedic surgeon towards the most appropriate treatment procedure.
评估骨单光子发射计算机断层扫描/计算机断层扫描（SPECT/CT）获得的定量值区分良性与恶性软骨性骨肿瘤的能力。
回顾性分析10例患者的骨SPECT/CT扫描结果，其中有8例良性软骨性骨肿瘤（4例内生软骨瘤、1例骨膜软骨瘤、1例骨软骨瘤、1例怪异型骨旁骨软骨瘤样增生、1例软骨母细胞瘤）和2例恶性软骨性骨肿瘤（1例骨膜软骨肉瘤、1例软骨肉瘤），分析原发灶的最大标准化摄取值（SUVmax）、平均SUV（SUVmean）、代谢骨体积（MBV）和总骨摄取量（TBU）。
8例良性和2例恶性软骨性骨肿瘤的平均SUVmax分别为1.93±1.02（范围0.59 - 3.41）和6.07±0.86（5.46 - 6.67），无重叠（P = 0.028）。两者的平均SUVmean分别为1.24±0.71（范围0.36 - 2.36）和4.05±0.30（3.84 - 4.26），无重叠（P = 0.00036）。两者的平均MBV分别为7.17±4.19（范围3.17 - 13.77）和10.29±10.05（3.19 - 17.4），无显著差异（P = 0.74）。两者的平均TBU分别为9.22±8.31（范围1.15 - 23.61）和43.19±43.7（12.26 - 74.13），无显著差异（P = 0.47）。
骨SPECT/CT获得的标准化摄取值可能有助于区分良性与恶性软骨性骨肿瘤，从而帮助骨科医生选择最合适的治疗方案。
