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Network Metamodeling: Effect of Correlation Metric Choice on Phylogenomic and Transcriptomic Network Topology.网络元建模:相关度量选择对系统发育基因组学和转录组学网络拓扑结构的影响。
Adv Biochem Eng Biotechnol. 2017;160:143-183. doi: 10.1007/10_2016_46.
2
3-way networks: application of hypergraphs for modelling increased complexity in comparative genomics.三路网络:超图在比较基因组学中建模增加的复杂性方面的应用。
PLoS Comput Biol. 2015 Mar 27;11(3):e1004079. doi: 10.1371/journal.pcbi.1004079. eCollection 2015 Mar.
3
Allele-specific network reveals combinatorial interaction that transcends small effects in psoriasis GWAS.等位基因特异性网络揭示了超越银屑病全基因组关联研究中小效应的组合相互作用。
PLoS Comput Biol. 2014 Sep 18;10(9):e1003766. doi: 10.1371/journal.pcbi.1003766. eCollection 2014 Sep.
4
A custom correlation coefficient (CCC) approach for fast identification of multi-SNP association patterns in genome-wide SNPs data.一种用于在全基因组单核苷酸多态性(SNP)数据中快速识别多SNP关联模式的自定义相关系数(CCC)方法。
Genet Epidemiol. 2014 Nov;38(7):610-21. doi: 10.1002/gepi.21833. Epub 2014 Aug 28.
5
Skewer: a fast and accurate adapter trimmer for next-generation sequencing paired-end reads.Skewer:一种用于新一代测序双端读段的快速且准确的接头修剪工具。
BMC Bioinformatics. 2014 Jun 12;15:182. doi: 10.1186/1471-2105-15-182.
6
voom: Precision weights unlock linear model analysis tools for RNA-seq read counts.voom:精确权重为RNA测序读数计数解锁线性模型分析工具。
Genome Biol. 2014 Feb 3;15(2):R29. doi: 10.1186/gb-2014-15-2-r29.
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Fold change rank ordering statistics: a new method for detecting differentially expressed genes.折叠变化等级排序统计:一种新的差异表达基因检测方法。
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STAR: ultrafast universal RNA-seq aligner.STAR:超快通用 RNA-seq 对齐工具。
Bioinformatics. 2013 Jan 1;29(1):15-21. doi: 10.1093/bioinformatics/bts635. Epub 2012 Oct 25.
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Comparative co-expression analysis in plant biology.植物生物学中的比较共表达分析。
Plant Cell Environ. 2012 Oct;35(10):1787-98. doi: 10.1111/j.1365-3040.2012.02517.x. Epub 2012 May 10.
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Phytozome: a comparative platform for green plant genomics.植物生物学数据库:一个用于绿色植物基因组学的比较平台。
Nucleic Acids Res. 2012 Jan;40(Database issue):D1178-86. doi: 10.1093/nar/gkr944. Epub 2011 Nov 22.

复杂数据集的网络建模。

Network Modeling of Complex Data Sets.

机构信息

Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.

The Bredesen Center for Interdisciplinary Research and Graduate Education, University of Knoxville Tennessee, Knoxville, TN, USA.

出版信息

Methods Mol Biol. 2020;2096:197-215. doi: 10.1007/978-1-0716-0195-2_15.

DOI:10.1007/978-1-0716-0195-2_15
PMID:32720156
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7963274/
Abstract

We demonstrate a selection of network and machine learning techniques useful in the analysis of complex datasets, including 2-way similarity networks, Markov clustering, enrichment statistical networks, FCROS differential analysis, and random forests. We demonstrate each of these techniques on the Populus trichocarpa gene expression atlas.

摘要

我们展示了一系列在分析复杂数据集时有用的网络和机器学习技术,包括双向相似网络、马尔可夫聚类、富集统计网络、FCROS 差异分析和随机森林。我们在胡杨基因表达图谱上演示了这些技术中的每一种。