Complejo Hospitalario de Navarra (CHN), Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008 Pamplona, Navarra, Spain.
Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Nutrients. 2020 Jul 26;12(8):2231. doi: 10.3390/nu12082231.
The objectives of this secondary analysis are (1) to investigate the differential effects of exercise training modalities-high-intensity interval training (HIIT), resistance training (RT), combined training (CT = HIIT + RT), and/or nutritional guidance (NG) alone-on local fat/lean mass indexes in adults with excess of adiposity; (2) to identify the individual patterns of response based on either a clinical criterion of weight loss (≥5%) and/or technical error (TE) of measurement of local fat/lean mass indexes; and (3) to assess the individual change for body composition parameters assigned either to HIIT, RT, CT, and/or NG groups utilizing a TE. A 12-week trial was conducted in 55 participants randomized to one of the four interventions. The primary outcome was clinical change in body weight (i.e., weight loss of ≥5%). Secondary outcomes included change in ratio of android and gynoid fat mass, as well as local fat and lean mass indexes (arms, trunk, and legs), before and after intervention. The main findings from the current analysis revealed that (i) after 12 weeks of follow-up, significant decreases in several body composition indexes were found including body weight, arm, trunk, and legs fat mass, and android and gynecoid fat mass were observed in HIIT, RT, and CT groups ( < 0.05); (ii) a significant proportion of individuals showed a positive response following 12 weeks of training, led by the HIIT group with 44% and followed by RT with 39% in 9 indexes; (iii) the HIIT group showed lowest rates of adverse responders with (6%); and (iv) the individual patterns of response utilizing clinically meaningful weight loss were not necessarily associated with the corresponding individual training-induced changes in body composition indexes in adults with excess of adiposity. Overall, the study suggests that HIIT has an important ability to reduce the prevalence of non-response to improve body composition indexes.
(1) 探究单独的运动训练方式——高强度间歇训练（HIIT）、抗阻训练（RT）、联合训练（CT=HIIT+RT）和/或营养指导（NG）对肥胖成年人局部脂肪/瘦体重指数的差异影响；(2) 根据体重减轻（≥5%）的临床标准和/或局部脂肪/瘦体重指数测量的技术误差（TE），确定个体的反应模式；(3) 利用 TE 评估分配给 HIIT、RT、CT 和/或 NG 组的身体成分参数的个体变化。这项为期 12 周的试验纳入了 55 名随机分配到四个干预组之一的参与者。主要结果是体重的临床变化（即体重减轻≥5%）。次要结果包括干预前后男性和女性身体脂肪比以及局部脂肪和瘦体重指数（手臂、躯干和腿部）的变化。当前分析的主要发现表明：（i）在 12 周的随访后，在 HIIT、RT 和 CT 组中观察到多个身体成分指数显著降低，包括体重、手臂、躯干和腿部脂肪量以及男性和女性脂肪量（<0.05）；（ii）经过 12 周的训练后，有相当比例的个体表现出积极的反应，其中 HIIT 组有 44%，RT 组有 39%，涉及 9 个指数；（iii）HIIT 组的不良反应者比例最低（6%）；（iv）利用具有临床意义的体重减轻的个体反应模式并不一定与肥胖成年人的相应个体训练引起的身体成分指数变化相关。总体而言，该研究表明 HIIT 具有重要的能力，可以降低非反应的发生率，从而改善身体成分指数。
