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超越基于阈值的二分分类法以提高对无反应者分类的准确性。

Moving beyond threshold-based dichotomous classification to improve the accuracy in classifying non-responders.

作者信息

Bonafiglia Jacob T, Nelms Matthew W, Preobrazenski Nicholas, LeBlanc Camille, Robins Lauren, Lu Simo, Lithopoulos Alexander, Walsh Jeremy J, Gurd Brendon J

机构信息

School of Kinesiology and Health Studies, Queen's University, Kingston, Ontario, Canada.

Healthy Active Living and Obesity Research Group, Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada.

出版信息

Physiol Rep. 2018 Nov;6(22):e13928. doi: 10.14814/phy2.13928.

DOI:10.14814/phy2.13928
PMID:30488594
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6429972/
Abstract

We examined maximal oxygen consumption responses following exercise training to demonstrate the limitations associated with threshold-based dichotomous classification of responders and non-responders and proposed alternative methods for classification. Specifically, we: 1) calculated individual probabilities of response, and 2) classified individuals using response confidence intervals (CI) and reference points of zero and a smallest worthwhile change of 0.5 METs. Our findings support the use of individual probabilities and individual CIs to improve the accuracy in non-response classification.

摘要

我们研究了运动训练后的最大耗氧量反应,以证明基于阈值的反应者和非反应者二分法分类的局限性,并提出了替代分类方法。具体而言,我们:1)计算个体反应概率,以及2)使用反应置信区间(CI)以及零和最小有价值变化0.5代谢当量的参考点对个体进行分类。我们的研究结果支持使用个体概率和个体置信区间来提高无反应分类的准确性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72f1/6429972/58bb89bb1be9/PHY2-6-e13928-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72f1/6429972/e112a2bdde39/PHY2-6-e13928-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72f1/6429972/58bb89bb1be9/PHY2-6-e13928-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72f1/6429972/e112a2bdde39/PHY2-6-e13928-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72f1/6429972/58bb89bb1be9/PHY2-6-e13928-g002.jpg

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