Department of Health Services Research, University of Tsukuba, Tsukuba, Ibaraki, Japan
Health Services Research and Development Center, University of Tsukuba, Tsukuba, Ibaraki, Japan.
BMJ Open. 2020 Jul 28;10(7):e036281. doi: 10.1136/bmjopen-2019-036281.
Because married couples have many environmental influences in common, spouses may develop similar diseases. This study aimed to determine the concordance of hypertension, diabetes and dyslipidaemia, which are major risk factors for cardiovascular disease, among married couples in Japan.
We conducted a cross-sectional study of married couples who were both aged ≥40 years using the 2016 Comprehensive Survey of Living Conditions, which is a Japanese national survey. We first determined the proportions of wives and husbands who were receiving therapy for each of the diseases of interest. We then conducted logistic regression analyses using the wives undergoing therapy for each disease as outcomes and the husbands undergoing therapy for the same disease as the principal exposure, adjusting for covariates.
The subjects of the analyses were 86 941 married couples. The wives of male patients were significantly more likely to be receiving therapy for the same disease. Logistic regression revealed that when husbands were undergoing therapy for these diseases their wives had ORs (95% CIs) of 1.79 (1.72-1.86) for hypertension, 1.45 (1.34-1.58) for diabetes, 2.58 (2.41-2.75) for dyslipidaemia and 1.87 (1.80-1.93) for any of these diseases.
If men have hypertension, diabetes or dyslipidaemia, their wives were also more susceptible to the same disease. Medical professionals and couples may need to recognise these results and consider couple-based interventions to help the prevention, early detection and treatment of these diseases.
由于已婚夫妇有许多共同的环境影响,因此他们可能会患上相似的疾病。本研究旨在确定日本已婚夫妇中高血压、糖尿病和血脂异常(心血管疾病的主要危险因素)的一致性。
我们使用 2016 年综合生活状况调查对年龄均≥40 岁的已婚夫妇进行了一项横断面研究,该调查是一项日本全国性调查。我们首先确定了妻子和丈夫分别接受每种疾病治疗的比例。然后,我们使用妻子接受每种疾病治疗的情况作为结局,以丈夫接受相同疾病治疗作为主要暴露,进行逻辑回归分析,调整了协变量。
分析的对象是 86941 对已婚夫妇。男性患者的妻子接受相同疾病治疗的可能性显著更高。逻辑回归显示,当丈夫接受这些疾病的治疗时,妻子患有高血压(95%CI:1.72-1.86)、糖尿病(95%CI:1.34-1.58)、血脂异常(95%CI:2.41-2.75)和任何一种这些疾病的比值比(OR)分别为 1.79、1.45、2.58 和 1.87。
如果男性患有高血压、糖尿病或血脂异常,那么他们的妻子也更容易患上同样的疾病。医疗专业人员和夫妇可能需要认识到这些结果,并考虑基于夫妇的干预措施,以帮助预防、早期发现和治疗这些疾病。