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一个由科学协会推动的结核病研究项目能有助于控制这种疾病吗?

[Can a tuberculosis research program promoted by a scientific society contribute to the control of the disease?].

作者信息

Rodrigo Sanz Teresa, Caylà Joan A, García-García José Mª

机构信息

Gestora de Proyectos del Programa Integrado de Investigación en Tuberculosis (PII-TB) de la Sociedad Española de Neumología y Cirugía Torácica (SEPAR). Barcelona. España.

Director del PII-TB de la SEPAR (2006-2016). Barcelona. España.

出版信息

Rev Esp Salud Publica. 2020 Jul 29;94:e202007089.

PMID:32724032
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11582860/
Abstract

Although Spain is a developed country, Tuberculosis (TB) was for years a disease with high incidence rates compared to other European countries, a situation that worsened with the HIV/AIDS epidemic and with the increase of immigration. The Spanish Respiratory Society (SEPAR) created in 2004 the Integrated Research Programs (PII) on respiratory diseases, including TB (PII-TB) which has carried out studies related to the five lines of research that it maintains: clinical / epidemiological, microbiological, technological/clinical management, evaluative, and international cooperation. Following the recommendations on the necessity to evaluate health programs made by international organizations, the evaluation of PII-TB was recently carried out, revealing the situation of the main variables of the disease and their evolution over the time that the program has been working. PII-TB has generated abundant data on the situation of this disease in our country in years when this information has been limited. The fact that the results of the studies have been widely disseminated makes it easier for all professionals involved in the prevention, diagnosis and treatment of TB to implement and/or to improve activities that, finally, will contribute to the control of this disease.

摘要

尽管西班牙是一个发达国家,但与其他欧洲国家相比,多年来结核病一直是一种高发病率的疾病,随着艾滋病毒/艾滋病疫情的蔓延以及移民数量的增加,这种情况变得更加严重。西班牙呼吸学会(SEPAR)于2004年设立了呼吸系统疾病综合研究项目(PII),其中包括结核病研究项目(PII-TB),该项目开展了与其所坚持的五条研究路线相关的研究:临床/流行病学、微生物学、技术/临床管理、评估以及国际合作。遵循国际组织关于评估卫生项目必要性的建议,最近对PII-TB进行了评估,揭示了该疾病主要变量的状况及其在项目实施期间的演变情况。在我国该疾病信息有限的年份里,PII-TB已经产生了大量关于该病状况的数据。研究结果得到广泛传播这一事实,使得所有参与结核病预防、诊断和治疗的专业人员更容易实施和/或改进相关活动,最终有助于控制这种疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ea1/11582860/6568b38a5cc0/1135-5727-resp-94-e202007089-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ea1/11582860/6214ed766518/1135-5727-resp-94-e202007089-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ea1/11582860/c2d4382f651d/1135-5727-resp-94-e202007089-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ea1/11582860/6568b38a5cc0/1135-5727-resp-94-e202007089-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ea1/11582860/6214ed766518/1135-5727-resp-94-e202007089-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ea1/11582860/c2d4382f651d/1135-5727-resp-94-e202007089-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ea1/11582860/6568b38a5cc0/1135-5727-resp-94-e202007089-g004.jpg

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本文引用的文献

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Evaluation of the Integrated Tuberculosis Research Program Sponsored by the Spanish Society of Pulmonology and Thoracic Surgery: 11 Years on.评价西班牙肺病学和胸外科学会赞助的结核病综合研究项目:11 年过去了。
Arch Bronconeumol (Engl Ed). 2020 Aug;56(8):483-492. doi: 10.1016/j.arbres.2019.10.006. Epub 2019 Nov 25.
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Comments on the SEPAR Guidelines for the Diagnosis and Treatment of Drug-Resistant Tuberculosis.关于耐多药结核病诊断与治疗的《SEPAR指南》评论
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Effectiveness and safety of bedaquiline-containing regimens in the treatment of MDR- and XDR-TB: a multicentre study.含贝达喹啉方案治疗耐多药和广泛耐药结核病的疗效和安全性:一项多中心研究。
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