人格障碍会增加精神状态障碍女性生活质量低的风险。
Personality disorder increases risk of low quality of life among women with mental state disorders.
机构信息
Deakin University, Institute for Physical and Mental Health and Clinical Translation School of Medicine, Barwon Health, Geelong, Victoria, Australia..
Deakin University, Institute for Physical and Mental Health and Clinical Translation School of Medicine, Barwon Health, Geelong, Victoria, Australia.; Florey Institute for Neuroscience and Mental Health, the University of Melbourne, Parkville, Victoria, Australia; The University of Melbourne, Department of Psychiatry, Royal Melbourne Hospital, Parkville, Victoria, Australia; Orygen, Melbourne, Victoria, Australia; Centre for Youth Mental Health, the University of Melbourne, Parkville, Victoria, Australia; Barwon Health, Geelong, Victoria, Australia; Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
出版信息
Compr Psychiatry. 2020 Oct;102:152193. doi: 10.1016/j.comppsych.2020.152193. Epub 2020 Jul 12.
BACKGROUND
Limited data are available examining the relationship between mental state disorders (mood, anxiety, substance use, eating disorders), their co-occurrence with personality disorder (PD), and quality of life among women. We aimed to investigate these relationships in a sample of women from the community.
METHOD
Women from the Geelong Osteoporosis Study (n = 717) were administered the Structured Clinical Interview for DSM-IV (SCID-I/NP and SCID-II) and the World Health Organisation Quality of Life scale (WHOQOL-BREF). Weight and height were measured and lifestyle and demographic factors were self-reported. Logistic regression models (odds ratios with 95% confidence intervals) were undertaken to investigate associations among groups (mental state disorders, co-occurring mental state disorders with PD, and controls) and the WHOQOL-BREF domains (physical, psychological, social, and environmental health) while testing for potential confounding.
RESULTS
Results indicated that mental state disorders were associated with increased risk of low quality of life in physical, psychological, social, but not environmental domains, compared to controls. This risk was increased among women with co-occurring PD across all domains compared to both controls and those with mental state disorders.
CONCLUSION
These findings add evidence suggesting poor quality of life is experienced by those with mental state disorders, and that this is worsened by the experience of co-occurring PD.
背景
目前关于精神障碍（情绪、焦虑、物质使用、饮食障碍）及其与人格障碍（PD）共病与女性生活质量之间关系的研究数据有限。我们旨在对社区中的女性样本研究这些关系。
方法
对来自 Geelong 骨质疏松研究（n=717）的女性进行 DSM-IV 结构临床访谈（SCID-I/NP 和 SCID-II）和世界卫生组织生活质量量表（WHOQOL-BREF）测试。测量体重和身高，并自我报告生活方式和人口统计学因素。进行逻辑回归模型（比值比和 95%置信区间），以研究精神状态障碍组（精神状态障碍、与 PD 共病的精神状态障碍和对照组）与 WHOQOL-BREF 各领域（身体、心理、社会和环境健康）之间的关联，同时测试潜在的混杂因素。
结果
结果表明，与对照组相比，精神状态障碍与生活质量下降的风险增加有关，在身体、心理和社会领域，但在环境领域没有。与对照组和精神状态障碍组相比，PD 共病的女性在所有领域的风险均增加。
结论
这些发现进一步证明，精神状态障碍患者的生活质量较差，而 PD 共病的经历则使情况恶化。
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