Sarkar Taranika, Jagroop Sophia
Jamaica Hospital Medical Center, Internal Medicine, Richmond Hill, NewYork, NY 11418, USA.
Case Rep Med. 2020 Jul 14;2020:3437465. doi: 10.1155/2020/3437465. eCollection 2020.
Pancreatic Divisum (PD) is the most common congenital variation of pancreatic duct anatomy, arising when embryological ventral and dorsal endodermal buds fail to fuse ("classic" PD) or only fuse partially ("incomplete" PD). Most patients with PD are asymptomatic, but a subgroup of patients can present with recurrent bouts of pancreatitis. While alcohol and gallstones are the common causes of acquired pancreatitis, PD is a congenital cause of pancreatitis. It is usually suspected in younger individuals with recurrent pancreatitis who also have a family history. Here, we present a rare case of PD in an older individual who presented with recurrent pancreatitis. He underwent cholecystectomy for suspected gallstone pancreatitis but continued to have episodes of pancreatitis. He had a history of alcohol abuse but denied use in the last one year. PD was detected later as the cause. Recurrent pancreatitis led to the development of a pseudocyst and pancreaticopleural fistula (PPF). Medical management improved the pseudocyst and PPF.
胰腺分裂(PD)是胰腺导管解剖结构最常见的先天性变异,当胚胎期腹侧和背侧内胚层芽未能融合(“经典”PD)或仅部分融合(“不完全”PD)时出现。大多数PD患者无症状,但有一小部分患者会反复出现胰腺炎发作。虽然酒精和胆结石是后天性胰腺炎的常见病因,但PD是胰腺炎的先天性病因。它通常在患有复发性胰腺炎且有家族史的年轻个体中被怀疑。在此,我们报告一例老年个体患PD并伴有复发性胰腺炎的罕见病例。他因疑似胆结石性胰腺炎接受了胆囊切除术,但胰腺炎仍反复发作。他有酗酒史,但否认在过去一年中有饮酒。后来发现PD是病因。复发性胰腺炎导致了假性囊肿和胰胸膜瘘(PPF)的形成。药物治疗改善了假性囊肿和PPF。