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胰腺分裂患者的腹侧胰腺炎。

Ventral pancreatitis in a patient with pancreas divisum.

作者信息

Sanada Y, Yoshizawa Y, Chiba M, Nemoto H, Midorikawa T, Kumada K

机构信息

Department of Surgery, Showa University Fujigaoka Hospital, Yokohama, Japan.

出版信息

J Pediatr Surg. 1995 May;30(5):665-7. doi: 10.1016/0022-3468(95)90685-1.

DOI:10.1016/0022-3468(95)90685-1
PMID:7623223
Abstract

Pancreas divisum results in drainage of most pancreatic secretions through the minor papilla via the dorsal duct, and the association of minor papilla stenosis has been implicated as a cause of pancreatitis. Most of the reported cases represent pancreatitis confined to the dorsal part. The authors treated a 10-year-old boy with recurrent pancreatitis that was substantially more severe in the ventral part. The patient was referred with a brief history of abdominal pain and had undergone a laparotomy when segmental ventral pancreatitis had been observed. Severe pancreatitis and acute renal failure developed, which required drainage of the lesser sac and hemodialysis, respectively. After 5 months, he had another episode that subsequently led to a pseudocyst in the ventral part. Endoscopic retrograde cholangiopancreatography via minor papilla showed a normal-caliber dorsal duct communicating with a part of the fine ventral ducts. A normal biliary tree was shown, but no ventral duct was visualized by cannulation to the major papilla of Vater. Dual sphincteroplasties and a cholecystectomy were performed. The minor papilla was stenotic and admitted only the finest lacrimal duct probe. The orifice of the ventral duct could not be observed. Thus it was clarified that the dorsal duct with its stenotic orifice had drained both the dorsal and ventral pancreas. The patient has remained asymptomatic over 36 months postoperatively. Despite their limited experience, the authors believe that (1) this anatomic variant led to ventral pancreatitis, and (2) the sphincteroplasty of the minor papilla was successful.

摘要

胰腺分裂导致大多数胰腺分泌物通过背侧导管经小乳头引流,小乳头狭窄被认为是胰腺炎的一个病因。大多数报道的病例表现为局限于背侧部分的胰腺炎。本文作者治疗了一名10岁复发性胰腺炎男孩,其腹侧胰腺炎病情严重得多。该患者因腹痛病史简短前来就诊,在观察到节段性腹侧胰腺炎时已接受剖腹手术。分别出现了严重胰腺炎和急性肾衰竭,前者需要小网膜囊引流,后者需要血液透析。5个月后,他又发作了一次,随后腹侧出现假性囊肿。经小乳头的内镜逆行胰胆管造影显示,正常管径的背侧导管与部分纤细的腹侧导管相通。胆管树正常,但通过向Vater主乳头插管未显示腹侧导管。实施了双重括约肌成形术和胆囊切除术。小乳头狭窄,仅能通过最细的泪道探针。未观察到腹侧导管开口。因此明确了狭窄开口的背侧导管引流了背侧和腹侧胰腺。术后36个月患者一直无症状。尽管经验有限,作者认为:(1)这种解剖变异导致了腹侧胰腺炎;(2)小乳头括约肌成形术是成功的。

相似文献

1
Ventral pancreatitis in a patient with pancreas divisum.胰腺分裂患者的腹侧胰腺炎。
J Pediatr Surg. 1995 May;30(5):665-7. doi: 10.1016/0022-3468(95)90685-1.
2
Pancreas divisum and stenosis of the major and minor papillae in an 8-year-old girl: treatment by dual sphincteroplasty.一名8岁女孩的胰腺分裂及主、副乳头狭窄:双括约肌成形术治疗
J Pediatr Surg. 1998 May;33(5):789-91. doi: 10.1016/s0022-3468(98)90223-8.
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Pancreas divisum: results of minor papilla sphincterotomy.胰腺分裂症:小乳头括约肌切开术的结果
Gastrointest Endosc. 1993 Jan-Feb;39(1):1-8. doi: 10.1016/s0016-5107(93)70001-2.
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The cause and treatment of pancreatitis associated with pancreas divisum.胰腺分裂相关胰腺炎的病因及治疗
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[Endoscopic therapy of pancreas divisum].[胰腺分裂症的内镜治疗]
Orv Hetil. 1998 Nov 15;139(46):2761-4.
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Neuroendocrine carcinoma of the minor papilla with pancreas divisum: a case report and review of the literature.胰腺分隔伴小乳头神经内分泌癌:病例报告及文献复习。
J Med Case Rep. 2023 Mar 28;17(1):127. doi: 10.1186/s13256-023-03828-x.
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Evaluation and treatment of the dominant dorsal duct syndrome (pancreas divisum redefined).主导背侧导管综合征的评估与治疗(重新定义的胰腺分裂症)
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[Pancreas divisum and the dominant dorsal duct syndrome].[胰腺分裂与主胰管综合征]
Ann Chir. 2005 Jan;130(1):5-14. doi: 10.1016/j.anchir.2004.11.010.

引用本文的文献

1
Incidence and Clinical Implications of Anatomical Variations in the Pancreas and Its Ductal System: A Systematic Review and Meta-Analysis.胰腺及其导管系统解剖变异的发生率及临床意义:一项系统评价与Meta分析
Life (Basel). 2023 Aug 9;13(8):1710. doi: 10.3390/life13081710.
2
Intraductal papillary mucinous carcinoma of the pancreas associated with pancreas divisum: a case report and review of the literature.胰腺导管内乳头状黏液性癌合并胰腺分裂症:一例报告及文献复习
BMC Gastroenterol. 2015 Jul 8;15:78. doi: 10.1186/s12876-015-0313-3.
3
The course of traumatic pancreatitis in a patient with pancreas divisum: a case report.
胰腺分裂症患者创伤性胰腺炎的病程:一例报告
BMC Gastroenterol. 2003 Mar 14;3:4. doi: 10.1186/1471-230x-3-4.
4
Surgical management of recurrent pancreatitis in children with pancreas divisum.胰腺分裂患儿复发性胰腺炎的外科治疗
Ann Surg. 2000 Jun;231(6):899-908. doi: 10.1097/00000658-200006000-00015.