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瑞士户外猫抗钩端螺旋体抗体的血清学检测

Serological detection of anti-leptospiral antibodies in outdoor cats in Switzerland.

作者信息

Hässle Sarah Noëmi, Rodriguez-Campos Sabrina, Howard Judith, Speiser-Fontaine Christelle, Schuller Simone

机构信息

Department Clinical Veterinary Medicine, Division of Small Animal Internal Medicine, Vetsuisse Faculty, University of Bern, Länggassstrasse 128, CH-3001, Bern, Switzerland.

Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Länggassstrasse 122, CH-3012, Bern, Switzerland.

出版信息

Vet Anim Sci. 2019 Aug 27;8:100068. doi: 10.1016/j.vas.2019.100068. eCollection 2019 Dec.

DOI:10.1016/j.vas.2019.100068
PMID:32734085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7386758/
Abstract

Leptospirosis is endemic in Switzerland affecting a broad range of hosts. The aim of this study was to estimate the exposure of cats to in Switzerland. Plasma samples from 107 outdoor cats with an array of clinical problems were tested via microscopic agglutination test for the presence of anti-leptospiral antibodies against 12 serovars of 9 serogroups. Using a reciprocal cut-off titre of 1:100, an overall seroprevalence of 10.3% (95%CI 5.2-17.7) was observed. Seroreactivity against serovars Bratislava ( = 6), Australis (2), Pomona (3) and Copenhageni (1) was detected with reciprocal titres ranging from 1:100 to 1:800. The serologic status of the cats was independent of the disease group ( = 0.62). These results show that cats in Switzerland are commonly exposed to and confirm the importance of serogroup Australis in this region.

摘要

钩端螺旋体病在瑞士呈地方性流行,感染多种宿主。本研究的目的是评估瑞士猫感染钩端螺旋体的情况。通过显微镜凝集试验,对107只患有一系列临床问题的户外猫的血浆样本进行检测,以检测其针对9个血清群中12个血清型的抗钩端螺旋体抗体。采用1:100的反向截断滴度,观察到总体血清阳性率为10.3%(95%可信区间5.2 - 17.7)。检测到针对布拉迪斯拉发血清型(n = 6)、澳大利亚血清型(2)、波摩那血清型(3)和哥本哈根血清型(1)的血清反应性,反向滴度范围为1:100至1:800。猫的血清学状态与疾病组无关(P = 0.62)。这些结果表明瑞士的猫普遍接触钩端螺旋体,并证实了澳大利亚血清群在该地区的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3b0/7386758/97de7e1e03f6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3b0/7386758/97de7e1e03f6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3b0/7386758/97de7e1e03f6/gr1.jpg

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