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通过高分辨率二维电泳研究人类多态性载脂蛋白 - 低密度脂蛋白。

Human polymorphic APO-LDL investigated by high-resolution two-dimensional electrophoresis.

作者信息

De Benedictis G, Di Maio E, Rose G, Renis M, Brancati C, Tagarelli A

机构信息

Department of Cell Biology, University of Calabria, Arcavacata.

出版信息

Exp Clin Immunogenet. 1986;3(2):75-80.

PMID:3274049
Abstract

The APO part of a human polymorphic low density lipoprotein (LDL) was investigated by two-dimensional electrophoresis. Since these allotypic LDL were purified from sera by specific immunochromatography, the data presented here refer to only one molecular species of LDL. The two-dimensional electrophoresis revealed the presence of isoforms which were correlated to the serological phenotype. A hypothesis about APO-LDL gene organization is outlined.

摘要

通过二维电泳研究了人类多态性低密度脂蛋白(LDL)的载脂蛋白部分。由于这些异型LDL是通过特异性免疫色谱法从血清中纯化得到的,因此此处呈现的数据仅涉及一种分子类型的LDL。二维电泳显示存在与血清学表型相关的同工型。概述了关于载脂蛋白-LDL基因组织的一种假说。

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