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一名新冠肺炎患者在接受抗凝治疗后仍发生重大血栓事件。

Major Thrombotic Event Despite Anticoagulation in a Patient With COVID-19.

作者信息

Ataallah Basma, Sharma Aman, Tamanna Sharmiz, Ng Joseph, Haggerty Gregory

机构信息

Internal Medicine, Zucker School of Medicine at Mather, Port Jefferson, USA.

Internal Medicine, Northwell Health Mather Hospital, Port Jefferson, USA.

出版信息

Cureus. 2020 Jun 29;12(6):e8896. doi: 10.7759/cureus.8896.

Abstract

The outbreak of coronavirus disease 2019 (known as COVID-19), which started in Wuhan, China in December 2019, is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has been associated with both venous and arterial thromboembolism likely secondary to significant cytokine activation and inflammation. Reports on the incidence of thrombotic complications, however, are not well documented. Our case will examine a young man diagnosed with COVID-19 who developed an acute, severe bilateral saddle pulmonary embolism while on prophylactic dose anticoagulation after being admitted to the hospital and treated for two weeks with significant improvement.

摘要

2019年冠状病毒病(简称COVID-19)于2019年12月在中国武汉爆发,由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起。它与静脉和动脉血栓栓塞有关,可能继发于显著的细胞因子激活和炎症。然而,关于血栓形成并发症发生率的报道记录并不充分。我们的病例将研究一名被诊断为COVID-19的年轻男性,他在入院接受治疗两周后病情有显著改善,但在接受预防性抗凝治疗时发生了急性、严重的双侧马鞍形肺栓塞。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6202/7389143/e71d9e6842c6/cureus-0012-00000008896-i01.jpg

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