Araújo Glauber R de S, Viana Nathan B, Gómez Fran, Pontes Bruno, Frases Susana
Laboratório de Ultraestrutura Celular Hertha Meyer, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Laboratório de Pinças Óticas (LPO-COPEA), Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Cell Surf. 2019 Aug 5;5:100028. doi: 10.1016/j.tcsw.2019.100028. eCollection 2019 Dec.
Microbes can modify their surface structure as an adaptive mechanism for survival and dissemination in the environment or inside the host. Altering their ability to respond to mechanical stimuli is part of this adaptive process. Since the 1990s, powerful micromanipulation tools have been developed that allow mechanical studies of microbial cell surfaces, exploring little known aspects of their dynamic behavior. This review concentrates on the study of mechanical and rheological properties of bacteria and fungi, focusing on their cell surface dynamics and biofilm formation.
微生物可以改变其表面结构,作为在环境中或宿主体内生存和传播的一种适应性机制。改变它们对机械刺激的反应能力是这一适应性过程的一部分。自20世纪90年代以来,已经开发出强大的微操纵工具,能够对微生物细胞表面进行力学研究,探索其动态行为中鲜为人知的方面。本综述集中于细菌和真菌的力学和流变学性质的研究,重点关注它们的细胞表面动态和生物膜形成。