Han Chang Hoon, Chung Jae Ho
Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
Department of Internal Medicine, International St. Mary's Hospital, Catholic Kwandong University College of Medicine, Incheon, Korea.
Ann Geriatr Med Res. 2018 Sep;22(3):145-150. doi: 10.4235/agmr.2018.22.3.145. Epub 2018 Sep 30.
The aim of this study was to determine whether the prevalence and extent of periodontal disease and tooth loss are increased in participants with sarcopenia.
This cross-sectional study included 8,053 males (sarcopenia, 2,772; nonsarcopenia, 5,281) and 10,729 females (sarcopenia, 3,085; nonsarcopenia, 7,644) ≥18 years of age who participated in the Korean National Health and Nutrition Examination Survey (KNHANES) from 2008 to 2011 and underwent assessments of oral health and appendicular skeletal muscle mass. Muscle mass index was calculated as appendicular muscle mass divided by height squared. The cutoff values for sarcopenia were 7.0 kg/m for males and 5.4 kg/m for females.
The group with sarcopenia brushed their teeth less frequently. The presence of periodontitis was significantly higher in participants with sarcopenia (males, 30.3%; females, 45.9%) than in participants without sarcopenia (males, 18.3%; females, 17.4%) (p<0.001). The number of natural teeth was significantly lower in participants with sarcopenia. The adjusted odds ratio for sarcopenia in participants with <20 natural teeth compared to those with full dentition was 1.96 (95% confidence interval [CI], 1.58-2.48) in males and 2.86 (95% CI, 2.31-3.56) in females. Subgroup analysis of the adjusted odds ratio for sarcopenia in older (≥65 years) individuals with <20 natural teeth was 1.92 (95% CI, 1.49-2.66) in males and 2.63 (95% CI, 2.25-3.64) in females.
Loss of the natural teeth wass significantly associated with sarcopenia.
本研究旨在确定肌肉减少症患者的牙周疾病患病率和严重程度以及牙齿脱落情况是否有所增加。
这项横断面研究纳入了8053名年龄≥18岁的男性（肌肉减少症患者2772名，非肌肉减少症患者5281名）和10729名女性（肌肉减少症患者3085名，非肌肉减少症患者7644名），他们参加了2008年至2011年的韩国国家健康与营养检查调查（KNHANES），并接受了口腔健康和附属骨骼肌质量评估。肌肉质量指数的计算方法为附属肌肉质量除以身高的平方。男性肌肉减少症的临界值为7.0kg/m，女性为5.4kg/m。
肌肉减少症组刷牙频率较低。肌肉减少症患者中牙周炎的患病率（男性为30.3%，女性为45.9%）显著高于非肌肉减少症患者（男性为18.3%，女性为17.4%）（p<0.001）。肌肉减少症患者的天然牙数量显著较少。与拥有完整牙列的参与者相比，天然牙少于20颗的男性参与者患肌肉减少症的校正比值比为1.96（95%置信区间[CI]，1.58 - 2.48），女性为2.86（95%CI，2.31 - 3.56）。对年龄≥65岁、天然牙少于20颗的个体进行亚组分析，男性患肌肉减少症的校正比值比为1.92（95%CI，1.49 - 2.66），女性为2.63（95%CI，2.25 - 3.64）。
天然牙缺失与肌肉减少症显著相关。
