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健康老年人、遗忘型轻度认知障碍患者及阿尔茨海默病患者的记忆信念、认知活动与抑郁状况比较

A Comparison of Memory Beliefs, Cognitive Activity, and Depression Among Healthy Older Adults, Amnestic Mild Cognitive Impairment, and Patient with Alzheimer's Disease.

作者信息

Park JongSik, Im Jooyeon Jamie, Song In-Uk, Kang Yeonwook

机构信息

Department of Neurology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.

Department of Radiology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.

出版信息

Ann Geriatr Med Res. 2019 Mar;23(1):16-19. doi: 10.4235/agmr.18.0051. Epub 2019 Mar 31.

Abstract

BACKGROUND

Amnestic mild cognitive impairment (aMCI) is highly likely to progress to dementia of the Alzheimer type (DAT). One of the most frequently reported symptoms in aMCI and DAT patients is memory impairment. This study compared the levels of beliefs about memory efficacy and control, cognitive activity, and depression among healthy older adults (OA), patients with aMCI, and patients with DAT.

METHODS

This study included 21 OA (11 males, 10 females), 16 aMCI patients (6 males, 10 females), and 18 DAT patients (10 males, 8 females). The memory efficacy questionnaire, memory control questionnaire, cognitive activity questionnaire, depression questionnaire, and Seoul Verbal Learning Test were administered to all subjects.

RESULTS

DAT patients showed significantly lower scores on the recognition test than did the OA and aMCI patients, and no difference in these scores was observed between the OA and aMCI patients. Regarding the memory efficacy, memory control, and cognitive activity questionnaires, DAT and aMCI patients showed significantly lower scores than did OA. However, there were no differences in these scores between aMCI and DAT patients.

CONCLUSION

The results of this study suggest that aMCI patients experienced impairment in memory beliefs and memory control in the same way as DAT patients did. These results suggest that the early application of cognitive rehabilitation therapy for patients with aMCI may be effective in preventing or alleviating memory deterioration.

摘要

背景

遗忘型轻度认知障碍(aMCI)极有可能发展为阿尔茨海默病型痴呆(DAT)。aMCI和DAT患者最常报告的症状之一是记忆障碍。本研究比较了健康老年人(OA)、aMCI患者和DAT患者在记忆效能信念、记忆控制、认知活动和抑郁方面的水平。

方法

本研究纳入了21名OA(11名男性,10名女性)、16名aMCI患者(6名男性,10名女性)和18名DAT患者(10名男性,8名女性)。对所有受试者进行了记忆效能问卷、记忆控制问卷、认知活动问卷、抑郁问卷和首尔言语学习测试。

结果

DAT患者在识别测试中的得分显著低于OA和aMCI患者,而OA和aMCI患者在这些得分上没有差异。在记忆效能、记忆控制和认知活动问卷方面,DAT和aMCI患者的得分显著低于OA。然而,aMCI和DAT患者在这些得分上没有差异。

结论

本研究结果表明,aMCI患者在记忆信念和记忆控制方面与DAT患者有相同程度的损害。这些结果表明,对aMCI患者早期应用认知康复治疗可能有效预防或减轻记忆衰退。

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Current concepts in mild cognitive impairment.轻度认知障碍的当前概念
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The role of demographic and life style variables in utilizing cognitive support for episodic remembering among very old adults.
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