绝经后妇女血清抵抗素水平与低骨密度的关系。
Serum resistin levels as predictor of low bone mineral density in postmenopausal women.
机构信息
Department of Physiology, University Medical & Dental College, Faisalabad, Pakistan.
Physiology and Cell Biology, University of Health Sciences, Lahore, Pakistan.
出版信息
Health Care Women Int. 2021 Jan;42(1):82-91. doi: 10.1080/07399332.2020.1798965. Epub 2020 Aug 3.
Resistin, a novel adipokine may play an important role in bone metabolism. The study is designed to discover the association of bone mineral density (BMD) with serum resistin levels, anthropometric measures and to elucidate serum resistin as a predictor of BMD in postmenopausal women. Postmenopausal women ( = 160) were recruited and divided into two groups, non-osteoporotic ( = 70) and osteoporotic ( = 90). BMD was evaluated by DXA scan. High serum resistin levels and low weight are independent contributors to low BMD and can influence BMD at lumbar spine, right femoral neck, right hip, left femoral neck, and left hip in postmenopausal women.
抵抗素，一种新的脂肪因子，可能在骨代谢中发挥重要作用。本研究旨在发现骨密度（BMD）与血清抵抗素水平、人体测量指标的关系，并阐明血清抵抗素是否可作为绝经后妇女 BMD 的预测因子。招募了 160 名绝经后妇女，并将其分为两组，非骨质疏松组（n=70）和骨质疏松组（n=90）。采用 DXA 扫描评估 BMD。高血清抵抗素水平和低体重是 BMD 降低的独立因素，可影响绝经后妇女腰椎、右侧股骨颈、右侧髋部、左侧股骨颈和左侧髋部的 BMD。
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